Results 71 to 80 of about 2,114,915 (360)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Groundwater Contamination [PDF]

open access: yes
This lesson addresses groundwater contamination from leakage of underground gasoline, oil, or other hazardous chemical tanks. Students read two short articles and investigate causes, effects, solutions, and prevention measures.
Christine McLelland
core   +4 more sources

The Economic Impacts of GM Contamination Incidents on the Organic Sector [PDF]

open access: yes, 2008
This paper examines the economic impact of GM co-existence on the global organic sector to date through GM contamination of organic food and crops. A total of 15 GM contamination incidents in the organic sector are identified, occurring either from cross-
Azeez, Ms Gundula, Hewlett, Ms Kathleen
core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Kinetic Study of Biodangerous Methylmercury Degradation under Various Light Conditions

open access: yesJournal of Chemistry, 2019
Methylmercury (MeHg) has remarkable toxicological effects on humans, plants, and other lives in the environment, which may restrict the comprehensive utilization of biomass source in view of possibly forming biohazardous waste.
Yutao Zhang   +4 more
doaj   +1 more source

Random contamination and select response styles affecting measures of fit and reliability in factor analysis [PDF]

open access: yes, 2017
This research examines the effects of nonattending response pattern contamination and select response style patterns on measures of model fit (CFI) and internal reliability (Cronbach's α). A simulation study examines the effects resulting from percentage
Harbaugh, A. G., Liu, Min
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Monitoring contamination level on insulator materials under dry condition with a microwave reflectometer [PDF]

open access: yes, 2016
Current techniques used for monitoring the levels of contamination on high voltage insulators, such as leakage current and infrared, are not effective in dry conditions since they require the surface of the insulator to be wetted by fog, rain or snow. If
Jiang, Y.   +5 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

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