Results 101 to 110 of about 13,919,687 (288)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Whose reading translates into mastery in English First Additional Language at Intermediate Phase?

Reading & Writing
Background: A large number of studies have established that reading for comprehension in South African schools is comparably poor relative to other Southern African states.
Thapelo Mokgadi, Muchativugwa L. Hove
doaj   +1 more source

Students Need More than Content Knowledge To Counter Vaccine Hesitancy. [PDF]

J Microbiol Biol Educ, 2023
Lee SW, Tran S.
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Collaboration and mutual support as processes established by communities of practice to improve continuing professional teachers’ development in high schools

Cogent Education, 2019
The purpose of the paper was to investigate how collaboration and mutual support as the processes established by communities of practice to improve continuing professional teachers’ development in high schools.
Adeola Folasade Akinyemi, Symphorosa Rembe, Jenny Shumba, Toyin Mary Adewumi   +3 more
doaj   +1 more source

Unravelling EFL teachers' mastery of TPACK: Technological pedagogical and content knowledge in writing classes. [PDF]

Heliyon, 2023
Abubakir H, Alshaboul Y.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The notions of floating and sinking: Exploring the conceptual knowledge of Grade R teachers

South African Journal of Childhood Education
Background: Preschool teachers play a key role in early scientific education, and their understanding and ability to communicate scientific concepts are crucial.
Mamontsuoe J.L. Maraisane, Loyiso C. Jita, Thuthukile Jita   +2 more
doaj   +1 more source