Results 101 to 110 of about 6,202,666 (342)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
HERMENEUTICAL PRINCIPLES OF QUALITY MANAGEMENT OF THE LABOR FORCEH [PDF]
Sovremennye Issledovaniâ Socialʹnyh Problem, 2012 The problem of quality of the workforce for the innovation economy is an extremely relevant and depends on the accepted ideology of quality management training.
Valentina Kiseleva
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
THE CHANGING FACE OF ORATURE IN POSTCOLONIAL NIGERIA
Proverbium, 2013 The coming into being of creative writing in English in post-colonial Nigeria since independence and the eminence attained in it as an expressive form by Achebe, Soyinka, Clark, Okigbo and many others, is a cultural revolution.
Nereus Yerima Tadi
doaj
Social prediction errors in assisting strangers: the role of outcomes and contexts
Frontiers in PsychologyIntroductionHelping behavior is a fundamental aspect of social interaction, yet little is known about how accurately helpers can predict the emotional responses of help-seekers, particularly when interacting with strangers.MethodsThis study investigated ...
Yan Li, Zhiwei Liu
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Guest editorial: Higher education research of master students: nurturing their development, hearing their voices, and promoting their expectations [PDF]
Higher Education Evaluation and DevelopmentHugo Horta, Jisun Jung
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Role of Contexts in Educational and Employment Transitions and Pathways of Young People
Social InclusionYoung people’s educational and employment pathways are shaped by the social contexts in which they are embedded. While past research has often emphasized individual characteristics, this thematic issue highlights the decisive role of contextual factors ...
Alexandra Wicht +3 more
doaj +1 more source