Results 131 to 140 of about 5,534,457 (290)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Efficacy of Modern Neuro-Evolutionary Strategies for Continuous Control Optimization. [PDF]
Front Robot AI, 2020 Pagliuca P, Milano N, Nolfi S.
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Uniformly Continuous Generalized Sliding Mode Control
MathematicsThis paper explores a general class of singular kernels with the objective of designing new families of uniformly continuous sliding mode controllers. The proposed controller results from filtering a discontinuous switching function by means of a Sonine ...
Aldo Jonathan Muñoz-Vázquez +1 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Control Power in Continuous Variable Controlled Quantum Teleportation
EntropyControlled quantum teleportation is an important extension of multipartite quantum teleportation, which plays an indispensable role in building quantum networks. Compared with discrete variable counterparts, continuous variable controlled quantum teleportation can generate entanglement deterministically and exhibit higher superiority of the supervisor ...
Yuehan Tian +7 more
openaire +3 more sources
Checkpoint blockade and the stem‐like T cell trade‐off
Molecular Oncology, EarlyView.Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley +1 more source
Wearable optomyography enables continuous neuroprosthetic control
Scientific ReportsWearable devices are increasingly used to enable human-machine interfaces, such as typing or cursor control, through wristbands that translate surface electromyographic (sEMG) signals into computer commands.
Roman Khalikov +3 more
doaj +1 more source