Results 81 to 90 of about 5,828,085 (378)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Scott & White Healthcare: Opening Up and Embracing Change to Improve Performance [PDF]
, 2010 Offers a case study of a multispeciality system with the attributes of an ideal healthcare delivery system as defined by the Fund. Describes a culture of continuous improvement, collaboration and peer accountability, and a comprehensive approach to ...
Douglas McCarthy, Kimberly Mueller
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Enterprise Agility: Why Is Transformation so Hard? [PDF]
, 2018 Enterprise agility requires capabilities to transform, sense and seize new business opportunities more quickly than competitors. However, acquiring those capabilities, such as continuous delivery and scaling agility to product programmes, portfolios and ...
Barroca, Leonor +2 more
core +1 more source
Pulsatile Pressure Delivery of Continuous Flow LVAD is Speed Dependent and Markedly Reduced Relative to Heart Failure Patients [PDF]
, 2022 Alan Rosenbaum +7 more
openalex +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Applying DevOps Practices of Continuous Automation for Machine Learning
Information, 2020 This paper proposes DevOps practices for machine learning application, integrating both the development and operation environment seamlessly. The machine learning processes of development and deployment during the experimentation phase may seem easy ...
Ioannis Karamitsos +2 more
doaj +1 more source
Affects of student attendance on performance in undergraduate materials and manufacturing modules [PDF]
, 2008 This paper investigates the class attendance of second year, third year and fourth year students and their overall performance at the school of Mechanical and Manufacturing Engineering in Dublin City University (DCU).
Brabazon, Dermot +2 more
core
Electrocardiographic patch devices and contemporary wireless cardiac monitoring. [PDF]
, 2015 Cardiac electrophysiologic derangements often coexist with disorders of the circulatory system. Capturing and diagnosing arrhythmias and conduction system disease may lead to a change in diagnosis, clinical management and patient outcomes.
Carlson, SK +9 more
core +2 more sources