Results 91 to 100 of about 14,224,726 (299)
On continuum models of ductile fracture [PDF]
Several fracture criteria are reviewed with respect to ductile fracture. It is suggested that both critical crack-tip displacement, 2Vc*, and critical fracture strain,∃*, criteria may describe the fracture of a ductile second phase rod in a ductile matrix.
openaire +2 more sources
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This paper investigates strain-, twist-, and electric-field-tuned optical absorption in bilayer MoS2, emphasizing spin-orbit coupling (SOC). A continuum model reveals competing mechanisms: geometric perturbations (strain/twist) and Stark effects govern ...
Lianmeng Yu +4 more
doaj +1 more source
Fractional contact model in the continuum
To appear in "Methods of Functional Analysis and Topology"
Kochubei, Anatoly, Kondratiev, Yurii
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Cournot–Nash equilibria in continuum games with non-ordered preferences. [PDF]
In the usual framework of continuum games with externalities, we substantially generalize Cournot–Nash existence results [Balder, A unifying approach to existence of Nash equilibria, Int.
Topuzu, Mihaela +1 more
core
Barlow-wu continuum systems: A discussion on the model
Barlow-Wu continuum structure functions have been introduced in the past as one particularly interesting family of continuum structure functions. In this paper we provide an alternative characterization for such continuum structure functions, showing ...
Yáñez Gestoso, Francisco Javier +1 more
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source

