Results 111 to 120 of about 75,941 (270)
Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction
eLife, 2016 Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown ...
Junqi Huang +9 more
doaj +1 more source
Identifying Cues that Regulate the Position of the Contractile Ring during Cytokinesis [PDF]
, 2013 Cytokinesis is the process where a mother cell cleaves into two daughter cells and is driven by the constriction of an actomyosin ring. Formation and ingression of the contractile ring is regulated by the mitotic spindle to couple cytokinesis with the ...
Akhshi, TK
core
, 2011 We created two new mutants of fission yeast cofilin to investigate why cytokinesis in many organisms depends on this small actin-binding protein. These mutant cofilins bound actin monomers normally, but bound and severed ADP-actin filaments much slower ...
Thomas D. Pollard, Qian Chen
core +1 more source
Strategic Design of Soft Actuators in Translational Medical Robotics for Human‐Centered Healthcare
Advanced Robotics Research, EarlyView.Soft robotics enables biocompatible, compliant medical devices, but clinical translation requires design‐driven engineering beyond materials. This perspective reviews implantable, surgical, and wearable systems by actuation mechanism, highlighting how optimized architectures and integration improve mechanical interfacing, adaptability, and durability ...
Ho Jun Jin +3 more
wiley +1 more source
Biology Open, 2017 When cells in epithelial sheets are damaged by intrinsic or extrinsic causes, they are eliminated by extrusion from the sheet. Cell extrusion, which is required for maintenance of tissue integrity, is the consequence of contraction of actomyosin rings ...
Sohei Yamada +4 more
doaj +1 more source
, 2015 SummaryCytokinesis in fission yeast cells depends on conventional myosin-II (Myo2) to assemble and constrict a contractile ring of actin filaments. Less is known about the functions of an unconventional myosin-II (Myp2) and a myosin-V (Myo51) that are ...
Hernandez-Leyva, Ariel +5 more
core +1 more source
Advances in Electroactive Liquid Crystal Elastomers for Intelligent Robotics and Electronics
Advanced Robotics Research, EarlyView.Electroactive liquid crystal elastomers (eLCEs) integrate molecular anisotropy with electrical functionality to enable programmable actuation and reconfigurable electronics. This review classifies eLCEs into robotic actuators and adaptive electronics, summarizes key actuation mechanisms, and highlights fabrication strategies that bridge materials to ...
Kavita Ramesh Rathod +14 more
wiley +1 more source
Cytokinesis requires localized β-actin filament production by an actin isoform specific nucleator
Nature Communications, 2017 Cytokinesis is initiated by the localized assembly of the contractile ring. Here the authors show that the stabilization and organization of the cytokinetic furrow requires localized β-actin filament assembly at the site of cytokinesis by an actin ...
A. Chen +3 more
doaj +1 more source
, 1998 We analyzed male meiosis in mutants of the chickadee (chic) locus, a Drosophila melanogaster gene that encodes profilin, a low molecular weight actin-binding protein that modulates F-actin polymerization.
BONACCORSI, Silvia +6 more
core +1 more source
Advanced Science, EarlyView.Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source