Results 201 to 210 of about 74,573 (237)

Genetic Biomarkers in the Risk Assessment of Sudden Cardiac Events: A Personalized Approach

iNew Medicine, EarlyView.
Genetic insights into the risk assessment of sudden cardiac events. ABSTRACT Sudden cardiac events are the leading cause of death worldwide. Conventional risk stratification methods, which largely depend on clinical history, imaging, and electrocardiography, are usually inadequate for identifying high‐risk individuals, especially those without visible ...
Shrikant Verma, Sushma Verma, Mohammad Abbas, Tabrez Faruqui, Bashir Ahmad Mir, Farzana Mahdi   +5 more
wiley   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, EarlyView.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

The fission yeast cytokinetic contractile ring regulates septum shape and closure.

J Cell Sci, 2015
Thiyagarajan S, Munteanu EL, Arasada R, Pollard TD, O'Shaughnessy B.   +4 more
europepmc   +1 more source

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Cytokinesis and the contractile ring in fission yeast

Current Opinion in Microbiology, 2001
The fission yeast Schizosaccharomyces pombe provides a genetic model system for the study of cytokinesis. As in many eukaryotes, cell division in the fission yeast requires an actin-myosin-based contractile ring. Numerous components of the contractile ring that function in ring assembly, positioning and contraction have been characterized.
Fred Chang
exaly   +3 more sources

The contractile ring

Cell and Tissue Research, 1970
Techniques of individual cell selection and precise ultramicrotomy have been employed to demonstrate that the contractile ring of cleaving HeLa cells is a transitory cytoplasmic organelle of distinctive fine structure and location. The contractile ring is an uninterrupted annulus encircling the equator of dividing cells exactly where the cleavage ...
exaly   +3 more sources

The role of microtubules in contractile ring function

Journal of Experimental Zoology, 1992
AbstractDuring cytokinesis, a cortical contractile ring forms around a cell, constricts to a stable tight neck and terminates in separation of the daughter cells. At first cleavage, Ilyanassa obsoleta embryos form two contractile rings simultaneously. The cleavage furrow (CF), in the animal hemisphere between the spindle poles, constricts to a stable ...
A H, Conrad, A Q, Paulsen, G W, Conrad
openaire   +2 more sources

Contractile ring composition dictates kinetics of in silico contractility

2022
Abstract Constriction kinetics of the cytokinetic ring are expected to depend on dynamic adjustment of ring composition, but the impact of component abundance dynamics on ring constriction is understudied. Computational models generally assume that contractile networks maintain constant composition.
Daniel B. Cortes, Francois Nedelec, Amy Shaub Maddox   +2 more
openaire   +1 more source

Dysphagia Produced by a Contractile Ring in the Lower Esophagus

Gastroenterology, 1953
Summary 1.In six male patients complaining of dysphagia, the responsible disorder appeared to be an annular esophageal constriction situated 0.5-2.5 cm. above the diaphragm. The constriction did not produce dysphagia unless it happened to trap a solid morsel of food, thereby occluding the esophageal lumen.
F J, INGELFINGER, P, KRAMER
openaire   +2 more sources

PUZZLING CONTRACTILE RINGS

Journal of Experimental Biology, 2003
![Figure][1] What is the driving force within a living cell that allows separation of daughter cells during cytokinesis? In many eukaryotes cell division requires the formation of a contractile ring, composed of actin and myosin filaments, that generates force to cleave the cell.
openaire   +1 more source