Results 81 to 90 of about 75,941 (270)
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Polar Body Emission Requires a RhoA Contractile Ring and Cdc42-Mediated Membrane Protrusion
, 2008 SummaryVertebrate oocyte maturation is an extreme form of asymmetric cell division, producing a mature egg alongside a diminutive polar body. Critical to this process is the attachment of one spindle pole to the oocyte cortex prior to anaphase. We report
Katbi, Hadia Arabi +5 more
core +1 more source
Emergence of dynamic contractile patterns in slime mold confined in a ring geometry
, 2022 International audienceAbstract Coordination of cytoplasmic flows on large scales in space and time are at the root of many cellular processes, including growth, migration or division.
Durand, Marc +2 more
core +1 more source
Writhing of Cytokinetic Contractile Rings Reveals that the Contractile Ring is an Elastoporous Cable [PDF]
Biophysical Journal, 2021 Sathish Thiyagarajan +6 more
openaire +1 more source
Advanced Healthcare Materials, EarlyView.Spontaneous helical alignment of smooth muscle cells is induced within resistance‐vessel‐sized channels patterned within a hydrogel. The extent of the cells’ orientation angle is dependent on the presence and composition of ECM proteins lining the channel wall and cell seeding density.
Victoria D. Vest +5 more
wiley +1 more source
, 2023 Projections of all focal planes after Imaris-mediated rotation to obtain ring-centric, more oocyte-end-on views of contractile ring dynamics in four each of control and mutant oocytes expressing GFP::NMY-2 (cyan) and mCherry:H2B (magenta) to mark NMY-2 ...
Alyssa R. Quiogue (17081666) +4 more
core +1 more source
eLife, 2018 To ensure timely cytokinesis, the equatorial actomyosin contractile ring constricts at a relatively constant rate despite its progressively decreasing size. Thus, the per-unit-length constriction rate increases as ring perimeter decreases.
Renat N Khaliullin +6 more
doaj +1 more source
On the role of mechanosensitive binding dynamics in the pattern formation of active surfaces
New Journal of Physics, 2022 The actin cortex of an animal cell is a thin polymeric layer attached to the inner side of the plasma membrane. It plays a key role in shape regulation and pattern formation on the cellular and tissue scale and, in particular, generates the contractile ...
M Bonati +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi +8 more
wiley +1 more source
Advanced Materials, EarlyView.SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung +6 more
wiley +1 more source