Results 1 to 10 of about 244,667 (356)

Contractile Vacuoles [PDF]

Nature, 1920
n ...
HENRY H. DIXON
  +8 more sources

Polyvinylphosphate Contractile Systems [PDF]

Nature, 1950
Riseman and Kirkwood1 recently suggested that the relaxation of muscle may be attributed to its stretching by the electrostatic repulsion of the ionized groups carried by the phosphorylated myosin molecules. During the contraction, the phosphate groups are split off, and the macromolecules coil up by Brownian movement.
Henryk Eisenberg, A. Katchalsky
openaire   +4 more sources

TRPV4 activation by TGFβ2 enhances cellular contractility and drives ocular hypertension [PDF]

eLife
The risk for developing primary open-angle glaucoma (POAG) correlates with the magnitude of ocular hypertension (OHT) and the concentration of transforming growth factor-β2 (TGFβ2) in the aqueous humor.
Christopher Nass Rudzitis, Monika Lakk, Ayushi Singh, Sarah N Redmon, Denisa Kirdajová, Yun-Ting Tseng, Michael L De Ieso, W Daniel Stamer, Samuel Herberg, David Krizaj   +9 more
doaj   +2 more sources

Weakly migratory metastatic breast cancer cells activate fibroblasts via microvesicle-Tg2 to facilitate dissemination and metastasis

eLife, 2022
Cancer cell migration is highly heterogeneous, and the migratory capability of cancer cells is thought to be an indicator of metastatic potential. It is becoming clear that a cancer cell does not have to be inherently migratory to metastasize, with ...
Samantha C Schwager, Katherine M Young, Lauren A Hapach, Caroline M Carlson, Jenna A Mosier, Tanner J McArdle, Wenjun Wang, Curtis Schunk, Anissa L Jayathilake, Madison E Bates, Francois Bordeleau, Marc A Antonyak, Richard A Cerione, Cynthia A Reinhart-King   +13 more
doaj   +1 more source

Hypercontractile cardiac phenotype in mice overexpressing the regulatory subunit PR72 of protein phosphatase 2A

Frontiers in Cardiovascular Medicine, 2023
BackgroundThe activity, localization, and substrate specificity of the protein phosphatase 2A (PP2A) heterotrimer are controlled by various regulatory B subunits.
Julius R. Herting, Jule H. König, Katarina Hadova, Alexander Heinick, Frank U. Müller, Paul Pauls, Matthias D. Seidl, Carolina Soppa, Uwe Kirchhefer   +8 more
doaj   +1 more source

Diverse integrin adhesion stoichiometries caused by varied actomyosin activity [PDF]

Open Biology, 2017
Cells in an organism are subjected to numerous sources of external and internal forces, and are able to sense and respond to these forces. Integrin-mediated adhesion links the extracellular matrix outside cells to the cytoskeleton inside, and ...
Natalia A. Bulgakova, Jutta Wellmann, Nicholas H. Brown   +2 more
doaj   +1 more source

The contractile ring [PDF]

Current Biology, 2003
What is it? The contractile ring is a ring-shaped structure located just beneath the plasma membrane at the future division site in many, though not all, eukaryotic cell types. Composed of actin, myosin and many other proteins, it assembles in anaphase and contracts as cells divide. The contractile ring is responsible for cytokinesis in many eukaryotic
Fred Chang, David R. Burgess
openaire   +3 more sources

Dexamethasone Treatment Preserves the Structure of Adult Cardiac Explants and Supports Their Long-Term Contractility In Vitro

International Journal of Translational Medicine, 2023
Normal contractile function of the myocardium is essential for optimal cardiovascular health. Evaluating drug effects on cardiomyocyte function at the cellular level is difficult for long-term studies.
Leonard M. Eisenberg, Keerat Kaur, John M. Castillo, John G. Edwards, Carol A. Eisenberg   +4 more
doaj   +1 more source

Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility. [PDF]

, 2018
Decreased contractility in the non-ischemic border zone surrounding a MI is in part due to degradation of cardiomyocyte sarcomeric components by intracellular matrix metalloproteinase-2 (MMP-2).
Aguayo, Esteban, Baker, Anthony J, Collins, Alexander, Faraji, Farshid, Ge, Liang, Lovett, David H, Ratcliffe, Mark B, Saloner, David, Spaulding, Kimberly, Takaba, Kiyoaki, Wallace, Arthur W, Wang, Guanying   +11 more
core   +13 more sources

Hypercontractile Cardiac Phenotype in Mice with Migraine-Associated Mutation in the Na⁺,K⁺-ATPase α₂-Isoform

Cells, 2023
Two α-isoforms of the Na+,K+-ATPase (α1 and α2) are expressed in the cardiovascular system, and it is unclear which isoform is the preferential regulator of contractility.
Rajkumar Rajanathan, Clàudia Vilaseca i Riera, Tina Myhre Pedersen, Christian Staehr, Elena V. Bouzinova, Jens Randel Nyengaard, Morten B. Thomsen, Hans Erik Bøtker, Vladimir V. Matchkov   +8 more
doaj   +1 more source