Results 91 to 100 of about 217,710 (307)
Maternal Cardiovascular Impairment in Pregnancies Complicated by Severe Fetal Growth Restriction [PDF]
, 2012 —Fetal growth restriction and preeclampsia are both conditions of placental etiology and associated to increased risk for the long-term development of cardiovascular disease in the mother. At presentation, preeclampsia is associated with maternal global
Liberati, M +3 more
core +1 more source
Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues
Advanced Healthcare Materials, EarlyView.Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman +7 more
wiley +1 more source
Different pathways involved in the stimulatory effects of homocysteine on rat duodenal smooth muscle
Acta Veterinaria, 2017 Recent studies have confirmed that hyperhomocysteinemia is associated with gastrointestinal diseases; however, the direct effect of homocysteine on gastrointestinal reactivity still remains unknown.
Stojanović Marija +8 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum +5 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundPigment epithelium‐derived factor (PEDF), which belongs to the noninhibitory serpin family, has shown the ability to stimulate several physiological processes, such as antiangiogenesis, anti‐inflammation, and antioxidation. In the present study,
Peng Lu +9 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham +11 more
wiley +1 more source
Assembly and positioning of actomyosin rings by contractility and planar cell polarity
eLife, 2015 The actomyosin cytoskeleton is a primary force-generating mechanism in morphogenesis, thus a robust spatial control of cytoskeletal positioning is essential.
Ivonne M Sehring +7 more
doaj +1 more source
Active Gel Model of Amoeboid Cell Motility
, 2013 We develop a model of amoeboid cell motility based on active gel theory. Modeling the motile apparatus of a eukaryotic cell as a confined layer of finite length of poroelastic active gel permeated by a solvent, we first show that, due to active stress ...
Callan-Jones, A. C., Voituriez, R.
core +1 more source
Advanced Healthcare Materials, EarlyView.Electrospun tubular scaffolds from novel PBCE‐based copolyesters and blends were designed as candidates for small‐diameter vascular grafts. They combine defect‐free architecture, blood‐compatible surfaces, and mechanical properties comparable to native vessels.
Edoardo Bondi +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This work pioneers melt electrowriting (MEW) of polyethylene vinyl acetate (PEVA) to fabricate ultra‐compliant, high‐resolution scaffolds. By integrating microscale precision with soft tissue‐like biomechanics, PEVA overcomes stiffness‐driven limitations of conventional MEW polymers, establishing a mechanically biomimetic platform for soft tissue ...
Finn Snow +9 more
wiley +1 more source