Results 21 to 30 of about 254,999 (359)

What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension [PDF]

open access: yes, 2015
The effects of increased intra-abdominal pressure (IAP) on cardiovascular function are well recognized and include a combined negative effect on preload, afterload and contractility.
De Keulenaer, Bart L   +2 more
core   +1 more source

Improved ventricular function during inhalation of PGI(2) aerosol partly relies on enhanced myocardial contractility [PDF]

open access: yes, 2005
Inhaled prostacyclin (PGI(2)) aerosol induces selective pulmonary vasodilation. Further, it improves right ventricular ( RV) function, which may largely rely on pulmonary vasodilation, but also on enhanced myocardial contractility.
B. Zwissler   +24 more
core   +1 more source

A novel method to extend viability and functionality of living heart slices

open access: yesFrontiers in Cardiovascular Medicine, 2023
Living heart slices have recently emerged as a powerful experimental model for fundamental cardiac research. By retaining the structure and function of the native myocardium while maintaining the simplicity of cell culture models, heart slices can be ...
Abigail J. Ross   +6 more
doaj   +1 more source

Phenotyping of Mice with Heart Specific Overexpression of A2A-Adenosine Receptors: Evidence for Cardioprotective Effects of A2A-Adenosine Receptors

open access: yesFrontiers in Pharmacology, 2018
Background: Adenosine can be produced in the heart and acts on cardiac adenosine receptors. One of these receptors is the A2A-adenosine receptor (A2A-AR).Methods and Results: To better understand its role in cardiac function, we generated and ...
Peter Boknik   +12 more
doaj   +1 more source

Regulation of pancreatic cancer aggressiveness by stromal stiffening [PDF]

open access: yes, 2016
No abstract ...
A Neesse   +13 more
core   +1 more source

Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation

open access: yesFrontiers in Physiology, 2019
Fascial tissues form a ubiquitous network throughout the whole body, which is usually regarded as a passive contributor to biomechanical behavior. We aimed to answer the question, whether fascia may possess the capacity for cellular contraction which, in
Robert Schleip   +12 more
doaj   +1 more source

Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane

open access: yesCells, 2023
A basic process in cancer is the breaching of basement-membrane barriers to permit tissue invasion. Cancer cells can use proteases and physical mechanisms to produce initial holes in basement membranes, but how cells squeeze through this barrier into ...
Shayan S. Nazari   +3 more
doaj   +1 more source

Child’s heart development and contractility from prenatal to postnatal period

open access: yesРоссийский кардиологический журнал, 2022
This literature review analyzes current data on the main stages of child’s heart contractility development from prenatal to postnatal period. The presented information will expand the conventional ideas on the age-related cardiovascular physiology in ...
E. N. Pavlyukova   +4 more
doaj   +1 more source

Contractility and Conformation [PDF]

open access: yesThe Journal of General Physiology, 1967
Contractility in fibers can arise from changes of macromolecular conformation caused by changes in some thermodynamic variable such as temperature, pH, or solvent composition. Illustrations are given of contractile processes in fibers and of changes in macromolecular conformation in dilute solution. These may involve order-disorder transitions, e.g. of
openaire   +2 more sources

Pigment Epithelium‐Derived Factor (PEDF) Improves Ischemic Cardiac Functional Reserve Through Decreasing Hypoxic Cardiomyocyte Contractility Through PEDF Receptor (PEDF‐R)

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundPigment epithelium‐derived factor (PEDF), which belongs to the noninhibitory serpin family, has shown the ability to stimulate several physiological processes, such as antiangiogenesis, anti‐inflammation, and antioxidation. In the present study,
Peng Lu   +9 more
doaj   +1 more source

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