Results 21 to 30 of about 244,667 (356)

Defective Autophagy in Vascular Smooth Muscle Cells Alters Vascular Reactivity of the Mouse Femoral Artery

open access: yesFrontiers in Physiology, 2020
Autophagy is an important cellular survival process that enables degradation and recycling of defective organelles and proteins to maintain cellular homeostasis.
Dorien G. De Munck   +5 more
doaj   +1 more source

Changes and classification in myocardial contractile function in the left ventricle following acute myocardial infarction [PDF]

open access: yes, 2017
In this research, we hypothesized that novel biomechanical parameters are discriminative in patients following acute ST-segment elevation myocardial infarction (STEMI).
Aderhold, Andrej   +5 more
core   +1 more source

Contractility and Conformation [PDF]

open access: yesThe Journal of General Physiology, 1967
Contractility in fibers can arise from changes of macromolecular conformation caused by changes in some thermodynamic variable such as temperature, pH, or solvent composition. Illustrations are given of contractile processes in fibers and of changes in macromolecular conformation in dilute solution. These may involve order-disorder transitions, e.g. of
openaire   +3 more sources

Phosphatidylinositol-3 kinase-Akt-mammalian target of rapamycin signaling pathway mediates contractility of human endometriotic stromal cells: A promising new target for the treatment of endometriosis-associated fibrosis

open access: yesGynecology and Minimally Invasive Therapy, 2014
Objective: To assess the involvement of phosphatidylinositol-3 kinase (PI3K)-Akt-mammalian target of rapamycin (mTOR) on the extracellular matrix contractility of endometriotic cells.
Wakana Abe   +4 more
doaj   +1 more source

Substrate stiffness and VE-cadherin mechano-transduction coordinate to regulate endothelial monolayer integrity. [PDF]

open access: yes, 2017
The vascular endothelium is subject to diverse mechanical cues that regulate vascular endothelial barrier function. In addition to rigidity sensing through integrin adhesions, mechanical perturbations such as changes in fluid shear stress can also ...
Andresen Eguiluz, Roberto C   +3 more
core   +1 more source

What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension [PDF]

open access: yes, 2015
The effects of increased intra-abdominal pressure (IAP) on cardiovascular function are well recognized and include a combined negative effect on preload, afterload and contractility.
De Keulenaer, Bart L   +2 more
core   +1 more source

Suppression of lusitropy as a disease mechanism in cardiomyopathies

open access: yesFrontiers in Cardiovascular Medicine, 2023
In cardiac muscle the action of adrenaline on β1 receptors of heart muscle cells is essential to adjust cardiac output to the body’s needs. Adrenergic activation leads to enhanced contractility (inotropy), faster heart rate (chronotropy) and faster ...
Steven Marston, Jose Renato Pinto
doaj   +1 more source

Phenotyping of Mice with Heart Specific Overexpression of A2A-Adenosine Receptors: Evidence for Cardioprotective Effects of A2A-Adenosine Receptors

open access: yesFrontiers in Pharmacology, 2018
Background: Adenosine can be produced in the heart and acts on cardiac adenosine receptors. One of these receptors is the A2A-adenosine receptor (A2A-AR).Methods and Results: To better understand its role in cardiac function, we generated and ...
Peter Boknik   +12 more
doaj   +1 more source

Fascia Is Able to Actively Contract and May Thereby Influence Musculoskeletal Dynamics: A Histochemical and Mechanographic Investigation

open access: yesFrontiers in Physiology, 2019
Fascial tissues form a ubiquitous network throughout the whole body, which is usually regarded as a passive contributor to biomechanical behavior. We aimed to answer the question, whether fascia may possess the capacity for cellular contraction which, in
Robert Schleip   +12 more
doaj   +1 more source

Child’s heart development and contractility from prenatal to postnatal period

open access: yesРоссийский кардиологический журнал, 2022
This literature review analyzes current data on the main stages of child’s heart contractility development from prenatal to postnatal period. The presented information will expand the conventional ideas on the age-related cardiovascular physiology in ...
E. N. Pavlyukova   +4 more
doaj   +1 more source

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