Results 81 to 90 of about 248,671 (308)

TNF-α induces VE-cadherin-dependent gap/JAIL cycling through an intermediate state essential for neutrophil transmigration

open access: yesFrontiers in Immunology
Inflammatory endothelial phenotypes describe distinct cellular patterns essential for controlling transendothelial migration of leukocytes (TEM). While TNF-α-induced CAM expression mediates leukocyte interaction, the role of a potential inflammatory ...
Jan Philip Kipcke   +13 more
doaj   +1 more source

Patterns in Space: Coordinating Adhesion and Actomyosin Contractility at E-cadherin Junctions

open access: yes, 2013
Cadherin adhesion receptors are fundamental determinants of tissue organization in health and disease. Increasingly, we have come to appreciate that classical cadherins exert their biological actions through active cooperation with the contractile actin ...
Wu, Selwin K., Yap, Alpha S.
core   +1 more source

A review of the molecular mechanisms underlying the development and progression of cardiac remodeling [PDF]

open access: yes, 2017
Pathological molecular mechanisms involved in myocardial remodeling contribute to alter the existing structure of the heart, leading to cardiac dysfunction.
Angelini, Francesco   +15 more
core   +3 more sources

Reconfigurable Microenvironments Uncover Mechano‐Sensing Timescales and Direct Cell Polarity

open access: yesAdvanced Functional Materials, EarlyView.
A synthetic DNA‐crosslinked cell culture matrix enables control over the mechanical microenvironment surrounding cells. Independent tuning of stiffness and stress relaxation uncovers distinct timescales of mechano‐sensing that regulate cell behavior.
Syuan‐Ku Hsiao   +4 more
wiley   +1 more source

Analysis of Contractility and Invasion Potential of Two Canine Mammary Tumor Cell Lines

open access: yesFrontiers in Veterinary Science, 2017
Cancer cells are surrounded by a mechanically and biochemically distinct microenvironment that undergoes dynamic changes throughout the neoplastic progression.
Kaisa Rajakylä   +2 more
doaj   +1 more source

Adaptations to iron deficiency: cardiac functional responsiveness to norepinephrine, arterial remodeling, and the effect of beta-blockade on cardiac hypertrophy. [PDF]

open access: yes, 2002
BackgroundIron deficiency (ID) results in ventricular hypertrophy, believed to involve sympathetic stimulation. We hypothesized that with ID 1) intravenous norepinephrine would alter heart rate (HR) and contractility, 2) abdominal aorta would be larger ...
Chew, Herbert George   +8 more
core   +1 more source

Bio‐Friendly Artificial Muscles Based on Carbon Nanotube Yarns and Eutectogel Derivatives

open access: yesAdvanced Functional Materials, EarlyView.
Solid‐state artificial muscles based on coiled commercial carbon nanotube yarns coated with eutectogel derivatives exhibit unipolar actuation through selective ion intercalation. Combining polyanionic and polycationic gels enables enhanced contractile stroke and high energy density.
Gabriela Ananieva   +6 more
wiley   +1 more source

CSE-Induced ER-Mitochondria Crosstalk Promotes Oxidative Stress and Impairs Bronchial Contractile Response

open access: yesAntioxidants
Chronic obstructive pulmonary disease (COPD), whose main risk factor is cigarette smoking, is among the most prevalent diseases worldwide. Previous studies have shown that cigarette smoke extract (CSE) can directly affect pulmonary artery function ...
Jorge Rodríguez-Pérez   +6 more
doaj   +1 more source

Long-Term Regulation of Excitation–Contraction Coupling and Oxidative Stress in Cardiac Myocytes by Pirfenidone

open access: yesFrontiers in Physiology, 2018
Pirfenidone (PFD) is used to treat human pulmonary fibrosis. Its administration to animals with distinct forms of cardiovascular disease results in striking improvement in cardiac performance.
Adrián Monsalvo-Villegas   +2 more
doaj   +1 more source

Soft Magnetic Artificial Muscles with High Work Density and Actuation Strain via Dual Cross‐Linking Design

open access: yesAdvanced Functional Materials, EarlyView.
A high‐performance magnetic composite actuator that integrates covalent and reversible physical cross‐links within a stiffness‐tunable polymer matrix embedded with functionalized magnetic particles is presented. The actuator exhibits programmable magnetic responsiveness, a stiffness switching ratio of 1.37 × 103, stretchability up to 1274%, large ...
Somi Kim   +7 more
wiley   +1 more source

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