Modeling drug retention as memory effects in obese patients using fractional and augmented models
Lipophilic anesthetic drugs accumulate in adipose tissue, leading to delayed release and prolonged effects, particularly in obese patients. This study proposes two novel physiologically motivated pharmacokinetic (PK) models to address these dynamics. The
Amani R. Ynineb +9 more
doaj +1 more source
Towards a methodology for rigorous development of generic requirements patterns
We present work in progress on a methodology for the engineering, validation and verification of generic requirements using domain engineering and formal methods.
Johnson, Ian +2 more
core
Reliability Analysis of Complex NASA Systems with Model-Based Engineering [PDF]
The emergence of model-based engineering, with Model- Based Systems Engineering (MBSE) leading the way, is transforming design and analysis methodologies.
Alimardani, Mahdi +2 more
core +1 more source
Design and implementation of a comprehensive management platform for drilling engineering. [PDF]
Du Y, Yang Y, Wu X, Gao P, Ma H.
europepmc +1 more source
Programmable spatiotemporal control of CRISPR-Cas12a: Engineering precision for next-generation gene editing and diagnostics. [PDF]
Seelan A +7 more
europepmc +1 more source
Yeast species resource exploration and application in cell factories. [PDF]
Zhang M, Xiang L, Qin L, Yue H, Li C.
europepmc +1 more source
Introduction to Nanoscale Advances in Innovative Bioengineering. [PDF]
Gu Z, Le Z, Su Z.
europepmc +1 more source
Vision-Controlled autonomous navigation in unstructured environments: Integrating image processing, path planning, and trajectory control in robotic systems. [PDF]
Wang P, Yu H, Wang S.
europepmc +1 more source
Resilient distributed model-free adaptive traffic signal control via controller dynamic linearization under DoS attacks. [PDF]
Ren Y +5 more
europepmc +1 more source
Rational engineering of combinatorial bacterial therapies for cancer. [PDF]
Steppe P, O'Connor K, Hasty J.
europepmc +1 more source

