Results 81 to 90 of about 15,651,541 (299)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Introduction to Extreme Seeking Entropy
Entropy, 2020 Recently, the concept of evaluating an unusually large learning effort of an adaptive system to detect novelties in the observed data was introduced. The present paper introduces a new measure of the learning effort of an adaptive system.
Jan Vrba, Jan Mareš
doaj +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Reinforcement learning for control of flexibility providers in a residential microgrid
IET Smart Grid, 2019 The smart grid paradigm and the development of smart meters have led to the availability of large volumes of data. This data is expected to assist in power system planning/operation and the transition from passive to active electricity users. With recent
Brida V. Mbuwir +5 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The Helmholtz resonator with different types of necks
, 2023 46th International Congress and Exposition on Noise Control Engineering: Taming Noise and Moving Quiet, INTER-NOISE 2017, 27-30 August 2017, Hong Kong202311 bckwNot applicableRGCPublishedPublisher ...
Wang, X, Mak, CM, Shi, X, Cai, C
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Modelling and simulation of AC–DC hybrid distribution network based on flexible DC interconnection
The Journal of Engineering, 2018 AC and DC hybrid distribution network detailed modelling and multi-operation conditions of the simulation analysis will effectively support the distribution network project reliable and stable operation.
Liang Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Design of torque system for electric bicycle based on fuzzy PID
The Journal of Engineering, 2019 This article analyses the structure and working principle of the brushless DC motor, the advantages and disadvantages of PID regulation and fuzzy control are analysed as well, and puts forward the fuzzy PID motor control technology with both advantages ...
Yunhong Zheng +2 more
doaj +1 more source