Results 71 to 80 of about 703,458 (267)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Frequency Response Analysis of Buck-Boost Inverter

open access: yesMìkrosistemi, Elektronìka ta Akustika, 2019
The paper deals with processes analysis in inverter circuits. These processes are described by differential equations with periodical coefficients. Since control signals and voltages operating in an inverter circuit are independent theirs frequencies are
Igor Yevheniiovych Korotyeyev
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Experimental investigation of spillover effect in system of active vibration control [PDF]

open access: yesFME Transactions, 2014
Piezoelectric actuators are widely used in structural systems for active vibration control with the aim to enhance the performance of systems. The developed system of active vibration control consists of active structure, controller and high voltage ...
Jovanović Miroslav M.   +6 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Identification of the Interaction Coefficients in an Intraspecific Competition Model with Diffusion Terms

open access: yesJournal of Mathematics
In this paper, we are interested in identifying the coefficients of the interaction terms in a parabolic system, which describes two subpopulations of the same species competing for the same resources.
Yang Na   +3 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Nonlinear control of power coefficients in wind turbines

open access: yes, 2019
Wind speed above rated value causes high power and generator over speed. This leads to overloading and breakdown of the generator. As a result, control is required to maintain the desired generated electrical power. Many papers use the blade pitch angle, which is highly non-linear as control input to achieve this goal.
BADJIE, Alieu Khama, KALYON, Muammer
openaire   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

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