Results 71 to 80 of about 6,305 (264)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Aplicación de control adaptativo a modelo 2 gdl de helicóptero
Resumen: Este artículo presenta resultados de control adaptativo obtenidos en el marco de trabajo de los proyectos CROMAT y COMETS. Se presenta la técnica de red neuronal adaptativa desarrollada en (Calise et al., 2001) aplicada al control del modelo en ...
M. Béjar, C. Raimúndez
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
MODELACIÓN DINÁMICA NO LINEAL Y CONTROL DE EVAPORADORES EN LA INDUSTRIA AZUCARERA
En este trabajo se desarrolla un modelo matemático no lineal riguroso del tipo DAEM para simular el comportamiento de estado estacionario y dinámico de la etapa de evaporación en el Ingenio azucarero “MALCA “ de la Provincia de Loja en Ecuador.
Luis M. Peralta Suárez +2 more
doaj
CONTROL NO LINEAL DE UN TCSC PARA MEJORAR LA ESTABILIDAD DE UN SISTEMA DE POTENCIA
Este artículo presenta el diseño del sistema de control de un compensador en serie controlado por tiristores o TCSC (TCSC: Thyristor-Controlled Series Compensation), basado en la combinación de la técnica de linealización entradasalida y la teoría del ...
Eddie Araya Padilla
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Linealización entrada/salida de sistemas no lineales afines utilizando un filtro
La linealización Entrada/Salida (E/S), dentro del marco teórico del control geométrico, es una técnica madura para sistemas no lineales afines. Esta técnica cancela los términos no lineales de la planta, usando una retroalimentación de estado no lineal ...
Alberto Delgado
doaj
This article shows the application of multi-objective optimization techniques, both for the identification of parameters of a model and for the adjustment of controllers.
Victor Manuel Huilcapi Subia +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source

