Results 51 to 60 of about 2,605,132 (291)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Stability of impulsive switched systems with sampled‐data control

open access: yesIET Control Theory & Applications, 2021
This paper investigates the sampled‐data control of impulsive switched systems with asynchronous switching. The impulses are not required to synchronise the switching.
Jie Lian, Chunyang Li, Guisheng Zhai
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Flight evaluation of simultaneous actuator/sensor fault reconstruction on a quadrotor minidrone

open access: yesIET Control Theory & Applications, 2021
In view of the increase in the number of Unmanned Aerial Vehicles (UAVs) in the commercial and private sectors, it is imperative to make sure that such systems are safe, and thus resilient to faults and failures. This paper considers the numerical design
S. Waitman, H. Alwi, C. Edwards
doaj   +1 more source

Attenuation of Persistent L∞-Bounded Disturbances for Nonlinear Systems [PDF]

open access: yes, 1995
A version of nonlinear generalization of the L1-control problem, which deals with the attenuation of persistent bounded disturbances in L∞-sense, is investigated in this paper. The methods used in this paper are motivated by [23]. The main idea in the L1-
John C. Doylef   +3 more
core   +2 more sources

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

The sliding mode control approach design for nonholonomic mobile robots based on non‐negative piecewise predefined‐time control law

open access: yesIET Control Theory & Applications, 2021
In this paper, a novel trajectory tracking control method of nonholonomic mobile robots based on the non‐negative piecewise predefined‐time theorem is proposed.
Lixiong Lin   +5 more
doaj   +1 more source

Scheduling Dimension Reduction of LPV Models -- A Deep Neural Network Approach [PDF]

open access: yes, 2020
In this paper, the existing Scheduling Dimension Reduction (SDR) methods for Linear Parameter-Varying (LPV) models are reviewed and a Deep Neural Network (DNN) approach is developed that achieves higher model accuracy under scheduling dimension reduction.
casella   +9 more
core   +2 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

On bipartite consensus of linear MASs with input saturation over directed signed graphs: Fully distributed adaptive approach

open access: yesIET Control Theory & Applications, 2021
This paper studies the bipartite consensus problem with input saturation for general linear represents multi‐agent systems (MASs) with signed digraphs.
Xiaoya Nan, Yuezu Lv, Zhisheng Duan
doaj   +1 more source

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