Problem of optimal control system synthesis
Problem of control system synthesis is considered, when control depends from state space vector. Analytic and calculation problems of synthesis and paths for decision of them are focused.
A I Diveev
doaj
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Fault-tolerant cooperation for time-varying multi-vehicle systems with [inline-formula] schemes
This study dealt with the fault-tolerant cooperation problem for a class of time-varying multi-vehicle system with actuator faults under the mixed [inline-formula] structure.
Jiantao Shi +3 more
doaj +1 more source
Switching Hinf Control Synthesis Designs for Networked Control Systems
This paper investigates joint stabilization and disturbance attenuation problem of for a class of networked control systems subject to disturbance and packet dropout in the transmission channel. A condition for exponential stabilization of networked control systems under a given switching rule is derived by employing multiple Lyapunov-like functions. A
Ma, Dan, Dimirovski, Georgi M.
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A System-Level Approach to Controller Synthesis [PDF]
Biological and advanced cyberphysical control systems often have limited, sparse, uncertain, and distributed communication and computing in addition to sensing and actuation. Fortunately, the corresponding plants and performance requirements are also sparse and structured, and this must be exploited to make constrained controller design feasible and ...
Yuh-Shyang Wang +2 more
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Fuzzy filtering‐based fault detection for a class of discrete‐time conic‐type nonlinear systems
The authors investigates the problem of fuzzy fault detection filter (FFDF) design for a class of discrete‐time conic‐type nonlinear systems. By applying Takagi–Sugeno fuzzy models, the conic‐type dynamic FFDF system is established.
Jiancheng Wang, Shuping He
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

