Results 111 to 120 of about 17,312,778 (333)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Assessing the Influence of Sleep-Wake Variables on Body Mass Index (BMI) in Adolescents
Europe's Journal of Psychology, 2013 Recent work has established an association between overweight/obesity and sleep duration, suggesting that short sleep duration and timing of sleeping may lead to overweight.
Christoph Randler +2 more
doaj +1 more source
ControlVAE: Controllable Variational Autoencoder
, 2020 accepted by ...
Huajie Shao +7 more
openaire +3 more sources
Control variates for stochastic gradient MCMC [PDF]
, 2019 It is well known that Markov chain Monte Carlo (MCMC) methods scale poorly with dataset size. A popular class of methods for solving this issue is stochastic gradient MCMC (SGMCMC). These methods use a noisy estimate of the gradient of the log-posterior,
Baker, Jack +3 more
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
On efficient simulation in dynamic models [PDF]
Ways of improving the efficiency of Monte-Carlo (MC) techniques are studied for dynamic models. Such models cause the conventional Antithetic Variate (AV) technique to fail, and will be proved to reduce the benefit from using Control Variates with nearly
Paruolo Paolo, Abadir Karim M.
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Control Variates for the Metropolis-Hastings Algorithm
We propose new control variates for variance reduction in estimation of mean values using the Metropolis-Hastings algorithm. Traditionally, states that are rejected in the Metropolis-Hastings algorithm are simply ignored, which intuitively seems to be a ...
HUGO HAMMER, H�KON TJELMELAND
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Some New Perspectives on the Method of Control Variates
, 2000 The method of control variates is one of the most widely used variance reduction techniques associated with Monte Carlo simulation. This paper studies the method of control variates from several di#erent viewpoints, and establishes new connections ...
Peter W. Glynn, Roberto Szechtman
core