Results 121 to 130 of about 17,312,778 (333)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Duality for multiobjective variational control and multiobjective fractional variational control problems with pseudoinvexity [PDF]

open access: yesInternational Journal of Stochastic Analysis, 2006
A class of multiobjective variational control and multiobjective fractional variational control problems is considered, and the duality results are formulated. Under pseudoinvexity assumptions on the functions involved, weak, strong, and converse duality theorems are proved.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

PECULIARITIES OF HUMUS AND NITROGEN ECOLOGICAL STATE FOR STEPPE ZONE CHERNOZEMS OF THE NORTH CAUCASUS

open access: yesВ мире научных открытий, 2017
Purpose of the paper presented is to determine tendency and intensity for quantitative and qualitative changes in humus and nitrogen of chernozems. System approach to study natural objects is assumed as the basis for research methodology of humus and ...
Aleksei Alekseevich Novikov
doaj   +1 more source

t-Copula generation for control variates

open access: yesMathematics and Computers in Simulation, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hormann, Wolfgang, Sak, Halis
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A Multilevel Approach to Control Variates

open access: yes, 2008
Control variates are a popular technique for reducing the variance of Monte Carlo estimates. Recent literature has enlarged the set of potentially useful control variates. Still, finding an control variate that efficiently reduces estimation error can be
Adam Speight
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Using Large Ensembles of Control Variates for Variational Inference

open access: yesCoRR, 2018
Variational inference is increasingly being addressed with stochastic optimization. In this setting, the gradient's variance plays a crucial role in the optimization procedure, since high variance gradients lead to poor convergence. A popular approach used to reduce gradient's variance involves the use of control variates.
Tomas Geffner, Justin Domke
openaire   +3 more sources

Control Variates for Stochastic Simulation of Chemical Reaction Networks

open access: yes, 2019
Stochastic simulation is a widely used method for estimating quantities in models of chemical reaction networks where uncertainty plays a crucial role. However, reducing the statistical uncertainty of the corresponding estimators requires the generation ...
Luca Bortolussi   +5 more
core   +1 more source

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