Results 61 to 70 of about 2,374,663 (244)

Effects of preoperative β-blocker on blood loss and blood transfusion during spinal surgeries with sodium nitroprusside-controlled hypotension

Saudi Journal of Anaesthesia, 2012
Background: The present study sought to determine whether premedication with oral β-blocker before hypotensive anesthesia with sodium nitroprusside could improve the quality of surgical field, decrease the blood loss, and decrease the need for homologous
Yasser Mohamed Amr, Sabry M Amin
doaj   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

Effects of Transcutaneous Electrical Acupoint Stimulation Combined with General Anesthesia on Changes of Gastric Dynamics in Controlled Hypotension Dogs

针刺研究, 2011
Objective To observe the effect of transcutaneous electrical acupoint stimulation(TEAS) combined with general anesthesia on gastric dynamics in controlled hypotension dogs,so as to provide experimental evidence for compound acupuncture anesthesia.Methods
FANG Jian-qiao, ZHANG Le-le, SHAO Xiao-mei, LIAN Lin-li, YU Xiao-jing, DONG Zhen-hua, MO Ya-di   +6 more
doaj   +2 more sources

Effect Of Controlled Hypotension On Regional Cerebral Oxygen Saturation During Rhinoplasty: A Prospective Study

, 2016
The aim of this study was to investigate the effect of controlled hypotension on cerebral oxygen saturation (rSO(2)) using near infrared spectroscopy (NIRS) and evaluation of postoperative cognitive function in patients undergoing rhinoplasty.
Taş Tuna, Ayça, Beyaz, Serbülent Gökhan, Palabıyık, Onur, Tomak, Yakup, Ali Fuat Erdem, Gurkan Kayabasoglu, Yakup Tomak, Sakarya Üniversitesi/Tıp Fakültesi/Cerrahi Tıp Bilimleri Bölümü, Tuna, Ayça Taş, Onur Palabiyik, Serbulent Gokhan Beyaz, Ayca Tas Tuna   +11 more
core   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

Advanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang, Jian‐Tong Shen, Hua‐Hua Zhang, Si‐Qi Gao, Ji‐Ao Wang, Yue‐Ling Wang, Mei‐Ling Li, Zi‐Meng Liu, Yi‐Nan Zhang, Yan Li, Xu‐Yu Zhang   +10 more
wiley   +1 more source

Macrophage GLUD1 is Essential for Redox Balance and Immune Homeostasis in Cardiac Injury

Advanced Science, EarlyView.
Excessive free radical production and dysregulated immune responses are key contributors to myocardial ischemia‐reperfusion (IR) injury. Macrophage GLUD1 activity safeguards against HIF‐1α accumulation and maladaptive responses to IR‐induced ROS production.
Tingting Jin, Chaojie Lai, Qingyan Zhou, Ruilin Wang, Yiping Tong, Wentao Chen, Nikola Rabrenovic, Tingyu Zhang, Xinrong Ren, Chengchen Huang, Jiawen Chen, Ran Li, Luyang Yu, Massimiliano Mazzone, Wenbin Zhang, Guosheng Fu, Min Shang   +16 more
wiley   +1 more source

Permissive strategies in intensive care units: actual trends? [PDF]

Anesthesia and Pain Medicine
Permissive strategies in the intensive care unit (PSICU) intentionally allow certain physiological parameters to deviate from traditionally strict control limits to mitigate the risks associated with overly aggressive interventions. These strategies have
Rudin Domi, Filadelfo Coniglione, Gentian Huti, Krenar Lilaj   +3 more
doaj   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Comparison of Labetalol and Dexmedetomidine Infusions for Hypotensive Anaesthesia in Middle Ear Surgery: A Randomised Controlled Trial [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Hypotensive anaesthesia has become an inevitable choice for patients undergoing microscopic middle ear surgeries under general anaesthesia, especially to decrease the intraoperative bleeding leading to improved visibility and reduced ...
Purnendu Bikash Pramanik, Pijush Kanti Bera, Swapnadeep Sengupta   +2 more
doaj   +1 more source