Results 81 to 90 of about 4,232,192 (254)

Gastroresistant coating of HPC capsules prepared by Injection-Molding

, 2013
Pulsatile release capsules made of a swellable/ erodible polymer (HPC), prepared by injection molding, were preliminarily evaluated as substrates in coating processes.
E. Macchi, L. Zema, A. Gazzaniga, L. A. Felton   +3 more
core   +2 more sources

CNF/p(AM-co-KAA) Semi-Interpenetrating Network Hydrogel Fertilizer Carriers for Enhanced Nutrient Use Efficiency, Water Retention, and Salt–Alkali Resistance

Gels
Developing functional agricultural materials that synchronize nutrient release, water retention, and soil amendment is crucial to advancing resource-efficient, sustainable farming systems.
Jingxuan Pan, Yanhong Wang, Jingwei Wang, Weiwen Qiu, Qiang Xiao, Shuqi Dong   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Self-healing lignin-based coating for controlled-release fertilizers with enhanced damage resistance and stable nutrient release

Industrial Crops and Products
Lignin is the second most abundant biomass resource in the world; it contains abundant active groups and has great application potential as a coating in controlled-release fertilizers (CRFs).
Ziyao Li, Zekun Wang, Boning Su, Xiangjie Zhao, Junyin Li, Jiahui Liu, Denglun Chen, Ronglei Li, Guodong Xia, Yujie Sun, Yao Cheng, Yuanyuan Yao, Shugang Zhang, Tianlin Shen, Yuechao Yang   +14 more
doaj   +1 more source

Chitosan-NVP IPN hydrogels synthesised through photoinitiator-free photopolymerisation technique for drug delivery

, 2004
Interpenetrating polymer network (IPN) hydrogels of chitosan with N-vinylpyrrolidinone (NVP) as well as its copolymer with 2 -hydroxyethyl met hacrylate (HEMA) were synthesised through the photoinitiator - free photopolymerisation technique.
Swami, Salesh N., Ng, Loo-Teck
core  

Controlled-release nanotherapeutics : state of translation

, 2018
This is a review of nanotherapeutic systems, specifically those that exhibit controlled release of the encapsulated bioactive compound. The survey includes the delivery of a range of bioactive compounds, from lipophilic small molecules to hydrophilic ...
Yang Fei Tan, Subbu Venkatraman, Gordon Minru Xiong, Xiong, Gordon Minru, Tan, Yang Fei, Lao, Luciana Lisa, Luciana Lisa Lao, Venkatraman, Subbu   +7 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source