Results 251 to 260 of about 243,069 (278)

Comparison and evaluation of metagenomic next-generation sequencing (mNGS) and real-time PCR for the detection of <i>Mycobacterium tuberculosis</i>. [PDF]

Front Cell Infect Microbiol
Wang Y, Guo P, Chen Y, Zhu H, Yu X, Deng J.   +5 more
europepmc   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Overcoming Target Drift: Development and Validation of a One-Step TaqMan qPCR Assay for Epidemiological Surveillance of Carpione rhabdovirus Circulating in Southern China. [PDF]

Microorganisms
Huang Y, Huang Z, Wang H, Li X, Liu X, Lin H, Zhang Z, Chen X, Jian J, Sun H.   +9 more
europepmc   +1 more source

Universal Solvent Escape Strategies for Efficient Curing of Hydrogen‐Bond‐Rich 3D Printing Inks

Advanced Science, EarlyView.
This study developed a new 3D printing method for hydrogen‐bonded polymers by combining solvent replacement, nanoparticles, and optimized printing paths. This allows fast, precise scaffold fabrication. The scaffolds can be easily customized and release therapeutic agents slowly through protonation, enabling personalized bone, blood vessel, and nerve ...
Jie Chen, Qing Zhao, Wentao Fu, Weixian Chen, Xiaoqian Zhang, Gaiying Ye, Qinglei Meng, Liyuan Shao, Qian Ma, Lin Zhao, Ying Zhao, Weihua Guo   +11 more
wiley   +1 more source

New parajeilongviruses detected in bats but not in humans: assays for screening and diagnostic purposes. [PDF]

Arch Virol
Pulkkinen E, Jackson R, Joensuu R, Korhonen EM, Masika MM, Anzala O, Ogola JG, Webala PW, Lunn TJ, Forbes KM, Vapalahti O, Kinnunen T, Sironen T, Jääskeläinen AJ.   +13 more
europepmc   +1 more source

OCTN2 Activates a Non‐Canonical Carnitine Metabolic Pathway to Promote MASH‐HCC Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
In non‐MASH‐HCC, L‐carnitine promotes tumor progression primarily through its classical role in enhancing fatty acid oxidation (FAO). However, in MASH‐HCC, where FAO is markedly suppressed, L‐carnitine shifts from this canonical function to serve instead as an intracellular acetyl group buffer.
Chuqi Xia, Xiao Zhang, Jinze Li, Ning Xu, Sheng Hu, Qiyu Lu, Yuxuan Li, Taifu Xiao, Xu Li, Xue Wang, Kequan Xu, Daoming Liang   +11 more
wiley   +1 more source

Comparative analysis of commercial and "In-House" molecular tests for the detection of intestinal protozoa in stool samples. [PDF]

Parasit Vectors
Di Pietra G, Gargiulo R, Ortalli M, Petrullo L, Oliva E, Raglio A, Frigo A, Castagliuolo I, Besutti V.   +8 more
europepmc   +1 more source

Development of multiplex RT-PCR assays containing an internal amplification control for the detection of dicistro-, iflaviruses and CBPV in honey bees. Part 1 - assays design and optimization. [PDF]

Vet Res Commun
Zdańska D, Rzeżutka A, Pohorecka K.
europepmc   +1 more source

Development and evaluation of a hybrid capture-based NGS panel for comprehensive detection of respiratory pathogens. [PDF]

Sci Rep
Kim JA, Kim JM, Lee C, Kim IH, Lee D, Lee H, Jeong J, Kim EJ.   +7 more
europepmc   +1 more source

Comparative evaluation of human ß defensin-2 in GCF and microbial flora in subgingival plaque among patients treated with conventional orthodontic braces and aligners: a prospective clinical study. [PDF]

Dental Press J Orthod
Sharma A, Kumar M, Yadav E, Kumar S, Goyal M, Rastogi S.   +5 more
europepmc   +1 more source