Results 251 to 260 of about 3,251,371 (302)

Molecular detection of African horse sickness virus from selected areas in Ethiopia. [PDF]

Vet Anim Sci
Esey DF, Waktole H, Gelaye E, Alene DH, Minale HA.   +4 more
europepmc   +1 more source

Tumor‐Intrinsic HEXB Drives Endothelial‐To‐Mesenchymal Transition and Confers Resistance to Anti‐Angiogenic Therapy in Glioblastoma

Advanced Science, EarlyView.
This study elucidates how glioblastoma tumors develop resistance to anti‐VEGF therapy through endothelial‐to‐mesenchymal transition (Endo‐MT). The researchers identify a novel signaling pathway where tumor‐derived HEXB stabilizes HSP60 to drive this vascular reprogramming.
Tianqi Liu, Xin Chen, Tao Sun, Jianqi Wu, Haixu Yan, Xing Liu, Hongda Lin, Xiangyu Wang, Ziao Xiao, Yang Xu, Qiang Fu, Peng Cheng, Wen Cheng, Anhua Wu   +13 more
wiley   +1 more source

Use of Dried Blood Spots for Identifying Hepatitis E Infections in an Outbreak Setting. [PDF]

J Med Virol
Alvarez C, Nesbitt R, Asilaza KV, Sattonnet-Roche P, Wamala J, Das S, Haile M, Rull M, Gignoux E, Albela M, Rumunu J, Eckerle I, Ciglenecki I, Azman AS, Meyer B.   +14 more
europepmc   +1 more source

A Biomimetic cRGDyk‐Engineered Platelet Nanoplatform for ACAD11 Delivery to Trigger Pyroptosis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A biomimetic platelet nanoplatform (OE‐ACAD11@R‐PLT) is developed for targeted hepatocellular carcinoma immunotherapy. By selectively delivering therapeutic plasmids, this system induces mitochondrial dysfunction and triggers robust NLRP3/Caspase‐1/GSDMD‐mediated pyroptosis in tumor cells.
Hongyi Bao, Wei Feng, Wei Zong, Yi Li, Xinyue Qin, Xinyue Wang, Yubo Yang, Guanhua Chen, Yiting Hou, Xuan Tan, Lin Chen, Ming Zhang, Feng Wang   +12 more
wiley   +1 more source

Evaluation of false positive enteric viruses results from the BIOFIRE® FILMARRAY® gastrointestinal PCR panel. [PDF]

J Clin Virol
Chhabra P, Cates J, Bartlett E, Embury SA, Rizwan A, Williams FA, Kambhampati AK, Marconi VC, Epstein L, Jasarevic R, Kraft CS, Rodriguez-Barradas MC, Morones RG, Covarrubias MA, Beenhouwer DO, Goldin E, Brown ST, Pena I, Lucero-Obusan CA, Holodniy M, Gautam R, Mirza SA, Vinjé J, Surveillance Platform for Enteric and Respiratory Infectious Organisms at the VA (SUPERNOVA) AGE Surveillance Group.   +23 more
europepmc   +1 more source

A Dual‐Delivery System Designed to Overcome EV‐Mediated Ferroptosis Resistance for Efficient Solid Tumor Therapy

Advanced Science, EarlyView.
(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen, Zhenguo Cao, Zenan Wang, Liang Chen, Jiahao Zhang, Linjie Zeng, Boren Tan, Hengyuan Li, Jiashan Lai, Jiangchu Lei, Fanglu Chen, Peng Lin, Zhenxuan Shao, Zhan Wang   +13 more
wiley   +1 more source

The Evolution of Neoadjuvant Treatment for Resectable Esophageal Squamous Cell Carcinoma: Past Achievements, Current Standards, and Future Perspectives. [PDF]

Cancers (Basel)
Ujiie N, Taniyama Y, Sato C, Okamoto H, Ozawa Y, Ishida H, Unno M, Kamei T.   +7 more
europepmc   +1 more source

Comparison of third generation ELISA and conventional nested RT-PCR for detection of HCV among hemodialysis patients

Journal of Applied Pharmaceutical Science, 2014
openaire   +1 more source

Targeting Macrophage STING O‐GlcNAcylation via Small‐Molecule Allosteric Modulation for Psoriasis Therapy

Advanced Science, EarlyView.
Paeoniflorin allosterically targets the STING cyclic dinucleotide‐binding domain, stabilizes an inactive open conformation, and disrupts STING–OGT interaction to reduce Thr229 O‐GlcNAcylation and downstream signaling. This mechanism restrains myeloid STING activation, alleviates psoriasis‐like inflammation, and is supported by analyses of patient ...
Fang‐Fang Zhuo, Cheng‐Chen Hou, Wei Wang, Ya‐Xuan Zhu, Ling Li, Li‐Juan Liu, Chuan‐Jian Lu, Peng‐Fei Tu, Yang Liu, Rui‐Zhi Zhao, Ke‐Wu Zeng   +10 more
wiley   +1 more source

Development and Application of a Fluorescence Quantitative RT-PCR Assay for Detection of Group A Rotavirus Among Pigeons in China from 2023 to 2024. [PDF]

Viruses
Yu X, Zhang C, Chen L, Wang J, Liu Y, Chen Y, Li J, Hou G, Chang S, Sun L, Li Y.   +10 more
europepmc   +1 more source