Results 61 to 70 of about 1,082,063 (275)

Regional economic disparities in Colombia [PDF]

open access: yesInvestigaciones Regionales - Journal of Regional Research, 2009
This paper advances the analysis of regional income convergence inColombia, through the use of the income data recently estimated for the departments,the main subnational political units. The results show a polarization process betweenBogotá and the rest
Jaime Bonet, Adolfo Meisel
doaj  

A modified filter nonmonotone adaptive retrospective trust region method.

open access: yesPLoS ONE, 2021
In this paper, aiming at the unconstrained optimization problem, a new nonmonotone adaptive retrospective trust region line search method is presented, which takes advantages of multidimensional filter technique to increase the acceptance probability of ...
Xianfeng Ding, Quan Qu, Xinyi Wang
doaj   +1 more source

Convergence of large deviation estimators

open access: yes, 2015
We study the convergence of statistical estimators used in the estimation of large deviation functions describing the fluctuations of equilibrium, nonequilibrium, and manmade stochastic systems.
Angeletti, Florian   +2 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

An interior-point method for mpecs based on strictly feasible relaxations. [PDF]

open access: yes, 2004
An interior-point method for solving mathematical programs with equilibrium constraints (MPECs) is proposed. At each iteration of the algorithm, a single primaldual step is computed from each subproblem of a sequence.
Angel Víctor De Miguel   +4 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Innovation and Regional Technological Convergence

open access: yes, 2023
This open access book explores the role of innovation in technological convergence processes in the EU regional space and shifts the focus from absolute and conditional income convergence to technological convergence and its determinants. Presenting new theoretical and empirical evidence on the determinants and trajectory of the EU region’s development
Tomasz Kijek   +2 more
openaire   +3 more sources

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

SHAP-based interpretable machine learning for injury risk prediction in university football players: a multi-dimensional data analysis approach

open access: yesScientific Reports
Sports injury prediction is crucial for university football player health, yet existing research predominantly focuses on professional athletes and lacks interpretability.
Jiacheng Ma, Shengrui Liu, Yuting Pei
doaj   +1 more source

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