Results 111 to 120 of about 1,258,142 (306)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Digital conversations about depression among Hispanics and non-Hispanics in the US: A big‐data, machine learning analysis [PDF]
, 2021 Ruby Castilla‐Puentes +5 more
openalex +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Strategies for Conversation and Systems Analysis in Requirements Gathering: A Qualitative View of Analyst-Client Communication [PDF]
, 2000 This paper describes how strategies for conversation and systems analysis may operate in requirements gathering. The emergence of these concepts, whilst using grounded theory techniques to analyse a case study of analyst-client interaction is discussed ...
Urquhart, Cathy
core +1 more source
FEBS Open Bio, EarlyView.This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source
Conversation analysis, practitioner based research, reflexivity and reflective practice: Some exploratory remarks. [PDF]
, 2006 During the course of this paper we intend to explore some possibilities that relate to ethnomethodology, conversation analysis, reflexive practice and practitioner based research. We intend to explore the way in which conversation analysis may facilitate
Cardiff University +2 more
core
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Komunikowanie emocji w nocnych rozmowach radiowych w świetle paradygmatu analizy konwersacyjnej
Forum Lingwistyczne, 2017 Communicating Emotions in Radio Night Time Talk Shows in the Paradigm of Conversational Analysis Grażyna Stachyra raises the question of night-time radio talk shows, where partners in conversation express their emotions.
Grażyna Stachyra
doaj
Ethnomethodological conversation analysis and the study of assemblages. [PDF]
Front Sociol, 2023 Raudaskoski P.
europepmc +1 more source
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source