Results 91 to 100 of about 249,873 (283)
Using shared wavelength converters effectively in optical switching [PDF]
, 2013 As internet traffic will further increase in coming years, the current network infrastructure will have to grow along in terms of capacity. To this end, optical packet/burst switching have been proposed, allowing more efficient use of the available fiber
Bruneel, Herwig +2 more
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
IEEE AccessA fault detection method for power conversion circuits using thermal images and a convolutional autoencoder is presented. The autoencoder is trained on thermal images captured from a commercial power module at randomly varied load currents and augmented ...
Noboru Katayama, Rintaro Ishida
doaj +1 more source
Frequency to Analog Converter [PDF]
, 1970 Frequency to analog converters with unipolar field effect transistor for determining potential charge by pulse duration of input ...
Hagihara, F. S.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Pilot Protection for Converter-interconnected Lines Based on Multi-stage Mutation of Fault Current
Zhongguo dianliThe introduction of power electronic converters has altered the fault characteristics of the traditional power grids. Traditional differential protection is inadequate to meet protection requirements when AC lines experience faults, leading to reduced ...
Zhaoyi SHA +4 more
doaj +1 more source
Control for nuclear thermionic power source [PDF]
, 1978 A control for a power source which includes nuclear fuel interspersed with thermionic converters, is described. A power regulator maintains a substantially constant output voltage to a variable load, and a control circuit drives a neutron flux regulator ...
Sawyer, C. D.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Using an Integrated Script Control Unit (ISCU) to Assist the Power Electronics Education
Energies, 2017 An integrated script control unit (ISCU) is invented to work as the digital controller in power electronics educations. The ISCU mainly consists of two parts, a control board and computer software.
Zhigang Gao, Qi Lu
doaj +1 more source