Results 101 to 110 of about 249,873 (283)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Experimental Study and Comparative Analysis of Transients of Induction Motor with Soft Starter Startup

open access: yesAdvances in Electrical and Computer Engineering, 2010
This paper investigates the influence of the parameters of the machine and of the soft starter on the dynamics of the induction machine start. In order to evaluate the effects of this variation we have used a design of experiments (DOE).
POPA, G. N.   +3 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Evaluation of magnetic materials for static inverters and converters [PDF]

open access: yes, 1969
Program studies materials for use in static inverters and converters.
Frost, R. M.   +2 more
core   +1 more source

Squeezing as an irreducible resource

open access: yes, 1999
We show that squeezing is an irreducible resource which remains invariant under transformations by linear optical elements. In particular, we give a decomposition of any optical circuit with linear input-output relations into a linear multiport ...
P. Ring   +2 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A Comparative Study of Harmonic Distortion in Multicarrier Based PWM Switching Techniques for Cascaded H-Bridge Inverters

open access: yesAdvances in Electrical and Computer Engineering, 2016
Multicarrier based PWM switching patterns are commonly utilized to control Cascaded H-bridge (CHB) inverters. The main contribution of this paper is to comprehensively investigate the effect of various multicarrier based PWM techniques on harmonic ...
HAMEDANI, P., SHOULAIE, A.
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Effect of CO2 on material and energy in dephosphorization converters

open access: yes工程科学学报, 2016
Based on the characteristics of CO2 at high temperature, material and energy models for CO2 using in a dephosphoriza-tion converter were established to verify the feasibility of CO2 for oxidation reactions.
LI Zhi-zheng, ZHU Rong, ZHU Yi-qiang
doaj   +1 more source

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