Results 91 to 100 of about 100,639 (379)

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

FEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli, Alex Fissore, Edoardo Salladini, Eleonora Raccuia, Simonetta Oliaro‐Bosso, Alessia Ruggiero, Rita Berisio, Milagros Medina, Adrian Velazquez‐Campoy, Salvatore Adinolfi, Mauro Marengo   +10 more
wiley   +1 more source

Patofisiologi Kejang dan Perubahan Susunan Saraf Pusat pada Eklampsia

Jurnal Neuroanestesi Indonesia, 2013
Eklampsia merupakan komplikasi serius kehamilan yang menimbulkan berbagai komplikasi neurologis seperti nyeri kepala, gangguan penglihatan, mual, muntah, koma, dan kejang.
Emilzon Taslim
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

The Relationship between Iron Deficiency Anemia and Febrile Convulsion in 6-Month to 5-Year-Old Children in Hazrat Fatemeh Masomeh Educational and Treatment Center, Qom University of Medical Sciences, Iran

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2015
Background and Objectives: Febrile convulsion (FC) is the most common seizure disorder in children and is seen in 2-5% of children under 5 years of age. This study was performed to determine the relationship between febrile convulsion and iron deficiency
Mohsen Molla Mohammadi, Javad Tafaroji
doaj  

Impact of Maternal Helicobacter pylori Infection on Trace Elements (Copper, Iron and Zinc) and Pregnancy Outcomes [PDF]

, 2010
Background: H. pylori infection has been suggested to interfere with micronutrient metabolism and influence pregnancy outcomes. Objectives: This study therefore seeks to document the prevalence of H.
Akubugwo, EI, Ugwuja, EI
core  

CONVULSIVE TIC. [PDF]

JAMA: The Journal of the American Medical Association, 1905
n ...
openaire   +2 more sources

Convulsions in Children [PDF]

The Boston Medical and Surgical Journal, 1901
n ...
Bullard, William N., Townsend, Charles W.   +1 more
openaire   +2 more sources

The Role of Serum Zinc Level in Febrile Convulsion

, 2012
Objective: Although the mechanism of febrile con- vulsion is not yet clear, some changes in the level of trace elements such as zinc have been suggested to be responsible for the pathogenesis.
F. Pekun, E. Adal
semanticscholar   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Antiepileptic Potential of Justicia insularis Leaf Extract in Swiss Mice

Biology, Medicine & Natural Product Chemistry
Epilepsy is a prevalent neurological condition characterized by repetitive seizures, necessitating the exploration of efficacious treatments. Justicia insularis, a plant with a historical use in treating convulsions and epilepsy, has garnered attention ...
Nancy Elkanah, Michael Chuks Nnumolu, Jude Effiom Okokon, Uduak Peter Ise   +3 more
doaj   +1 more source