Results 61 to 70 of about 53,185 (257)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Driving Capability-Based Transition Strategy for Cooperative Driving: From Manual to Automatic

IEEE Access, 2020
In open traffic environments, humans still have to remain in the control loop of vehicle due to the insufficient of the existing technologies and their high costs. For the realization of cooperation between the human and the automatic driving system, the
Fengmin Tang, Feng Gao, Zilong Wang
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Communication Efficient Cooperative Perception via Codebook-Free Vector Quantization

IEEE Access
Recent advances in cooperative perception have demonstrated significant performance improvements over single-agent perception. In practice, cooperative perception methods often exchange intermediate multi-channel BEV feature maps at a high frame rate ...
Junjie Wang, Zeyu Gao, Tomas Nordstrom
doaj   +1 more source

Collision-Aware Communication for Intersection Management of Automated Vehicles

IEEE Access, 2018
Intersection management of automated vehicles relies on wireless communication, whereby communication resources should be allocated to vehicles while maintaining safety. We present a collision-aware resource allocation (CARA) strategy for coordination of
Erik Steinmetz, Robert Hult, Zhenhua Zou, Ragne Emardson, Fredrik Brannstrom, Paolo Falcone, Henk Wymeersch   +6 more
doaj   +1 more source

Assessment of Drivers’ Comprehensive Driving Capability Under Man-Computer Cooperative Driving Conditions

IEEE Access, 2020
The effective assessment of drivers' driving capability under the condition of an advanced driver assistance system is of great significance to the precise switching of driving rights between human and machine and the promotion of the development of man ...
Tao Wang, Yuzhi Chen, Xingchen Yan, Wenyong Li, Dong Shi   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

FedAV: Federated learning for cyberattack vulnerability and resilience of cooperative driving automation

Communications in Transportation Research
Cooperative driving automation (CDA) has gained attention over the years because of its cooperative driving capability that provides solution to individual automated driving challenges.
Guanyu Lin, Sean Qian, Zulqarnain H. Khattak   +2 more
doaj   +1 more source

Effectiveness Proving and Control of Platoon-Based Vehicular Cyber-Physical Systems

IEEE Access, 2018
With the application of cyber-physical systems, many cargo fleets take the initiative to form a platoon during transportation. Compared with the conventional signal timing algorithms, the platoon-based algorithm can greatly reduce the traveling time ...
Jia Wu, Fei Yan, Jianxing Liu
doaj   +1 more source