Results 1 to 10 of about 528,536 (311)

Beta defensin-2 is reduced in central but not in distal airways of smoker COPD patients [PDF]

, 2012
Background: Altered pulmonary defenses in chronic obstructive pulmonary disease (COPD) may promote distal airways bacterial colonization. The expression/activation of Toll Like receptors (TLR) and beta 2 defensin (HBD2) release by epithelial cells ...
A Aderem, A Biragyn, A Bruno, A Busacker, A Kato, AL Cozens, Angela Marina Montalbano, C Herr, CJ Murray, CY Kao, D Droemann, D Miotto, Dominik Hartl, E Doz, E Pace, E Pace, E Pace, E Pace, E Pace, Elisabetta Pace, F Niyonsaba, G Chiappara, Giuseppina Chiappara, J Pons, JC Hogg, JL Curtis, JL Imler, K Fellerman, K Kolble, L Petecchia, Liboria Siena, LM Hamilton, Loredana Pipitone, M Saetta, Malcolm Johnson, Maria Ferraro, Mark Gjomarkaj, Marta Ida Minervini, MG Cosio, N Kanda, Patrizio Vitulo, Q Sha, R MacRedmond, R O'Donnell, S Boodoo, S Sethi, S Sethi, SD Sullivan, TS Lapperre, V Kim, W Zhang, X Zhang   +51 more
core   +14 more sources

Editorial: Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Guidelines for COPD, Including COVID-19, Climate Change, and Air Pollution

Medical Science Monitor, 2023
The 2023 Global Initiative for Chronic Obstructive Lung Disease (GOLD) report includes relevant topics from the clinician’s perspective and evidence published on chronic obstructive pulmonary disease (COPD) since GOLD 2017. The World Health Organization (
D. Parums
semanticscholar   +1 more source

Developing a patient-driven chronic obstructive pulmonary disease (COPD) research agenda in the U.S.

Journal of Patient-Reported Outcomes, 2021
Plain English summary The COPD Patient-Powered Research Network (PPRN) asked adults with COPD and their caregivers to suggest areas for future research on COPD.
Inga Gruß, Gretchen M. McCreary, Ilya Ivlev, Mary Ellen Houlihan, Barbara P. Yawn, Cara Pasquale, William Clark, Richard A. Mularski   +7 more
doaj   +1 more source

Gut microbiota modulates COPD pathogenesis: role of anti-inflammatory Parabacteroides goldsteinii lipopolysaccharide

Gut, 2021
Objective Chronic obstructive pulmonary disease (COPD) is a global disease characterised by chronic obstruction of lung airflow interfering with normal breathing. Although the microbiota of respiratory tract is established to be associated with COPD, the
H. Lai, Tzu-Lung Lin, Ting-Wen Chen, Y. Kuo, Chih-Jung Chang, Tsung-Ru Wu, C. Shu, Ying-Huang Tsai, S. Swift, Chia-Chen Lu   +9 more
semanticscholar   +1 more source

The relation between age and airway epithelial barrier function

Respiratory Research, 2022
Background The prevalence of age-associated diseases, such as chronic obstructive pulmonary disease (COPD), is increasing as the average life expectancy increases around the world.
M. de Vries, K. O. Nwozor, K. Muizer, M. Wisman, W. Timens, M. van den Berge, A. Faiz, T.-L. Hackett, I. H. Heijink, C. A. Brandsma   +9 more
doaj   +1 more source

Knowledge and Attitudes Concerning Herpes Zoster among People with COPD: An Interventional Survey Study

Vaccines, 2022
Herpes zoster (HZ) is common in older adults with conditions such as chronic obstructive pulmonary disease (COPD). Effective prevention is available through vaccination, but HZ vaccine uptake remains incomplete. Using an online survey of people with self-
Barbara P. Yawn, Debora D. Merrill, Sergio Martinez, Elisabeth Callen, Janice Cotton, Dennis Williams, Natalia Y. Loskutova   +6 more
doaj   +1 more source

The impact of COPD and smoking history on the severity of COVID‐19: A systemic review and meta‐analysis

Journal of Medical Virology, 2020
Comorbidities are associated with the severity of coronavirus disease 2019 (COVID‐19). This meta‐analysis aimed to explore the risk of severe COVID‐19 in patients with pre‐existing chronic obstructive pulmonary disease (COPD) and ongoing smoking history.
Qianwen Zhao, Meng Meng, Rahul Kumar, Yinlian Wu, Jiaofeng Huang, N. Lian, Yunlei Deng, Su Lin   +7 more
semanticscholar   +1 more source

Prevalence, Severity and Mortality associated with COPD and Smoking in patients with COVID-19: A Rapid Systematic Review and Meta-Analysis

medRxiv, 2020
Background: Coronavirus disease 2019 (COVID-19) is an evolving infectious disease that dramatically spread all over the world in the early part of 2020.
J. Alqahtani, Tope Oyelade, A. Aldhahir, S. Alghamdi, M. Almehmadi, A. Alqahtani, S. Quaderi, S. Mandal, J. Hurst   +8 more
semanticscholar   +1 more source

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19

European Respiratory Journal, 2020
The World Health Organization (WHO) has declared coronavirus disease 2019 (COVID-19) a pandemic [1]. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
J. Leung, C. Yang, A. Tam, T. Shaipanich, T. Hackett, G. Singhera, D. Dorscheid, D. Sin   +7 more
semanticscholar   +1 more source

Addiction to tobacco smoking and vaping

Revista de Investigación Clínica, 2023
The tobacco epidemic has been one of the biggest public health threats, and smoking is one of the world’s largest preventable causes of premature death. An estimated 15.4% of all deaths in the world are attributable to tobacco smoking. The present review
Andrea Hernández-Pérez, Leonor García-Gómez, Robinson Robles-Hernández, Ireri Thirión-Romero, Jennifer Osio-Echánove, Sebastián Rodríguez-Llamazares, Ruben Baler, Rogelio Pérez-Padilla   +7 more
doaj   +1 more source