Results 21 to 30 of about 602,916 (384)
European Respiratory Review, 2013 By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality. Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco smoking is a common risk factor for many comorbidities, including coronary heart disease, heart failure and lung cancer.
Cavaillès, Arnaud +10 more
openaire +6 more sources
European Respiratory Review, 2019 Sphingolipids are a distinct class of lipid molecules widely found in nature, principally as cell membrane constituents. After initial uncertainty about their function, sphingolipids have been increasingly recognised to be metabolically active entities involved in many biological processes, including the control of inflammation. Their role as mediators
Raja Chandra Chakinala +4 more
openaire +3 more sources
Respiratory Medicine, 2005 The multicomponent nature of chronic obstructive pulmonary disease (COPD) has provided a challenging environment in which to develop successful treatments. A combination of pharmacological and non-pharmacological approaches is used to combat this problem, and an overview of these approaches and their possible future direction is given.
Hanania, Nicola A. +5 more
openaire +4 more sources
Economic Burden of Chronic Obstructive Pulmonary Disease (COPD): A Systematic Literature Review
International Journal of COPD, 2020 Background and Objectives Chronic obstructive pulmonary disease (COPD) affects over 250 million people globally, carrying a notable economic burden. This systematic literature review aimed to highlight the economic burden associated with moderate-to-very
I. Iheanacho +4 more
semanticscholar +1 more source
Breathe, 2020 Health inequalities regarding gender are extremely prevalent, and specifically in conditions such as COPD. No woman should ever be dismissed in regard to their health and underlying medical history. https://bit.ly/2X7Klmd.
Jessica Denning +3 more
openaire +3 more sources
Current concepts on the role of inflammation in COPD and lung cancer [PDF]
, 2009 Chronic obstructive pulmonary disease (COPD) and lung cancer are leading cause of death, and both are associated with cigarette smoke exposure. It has been shown that 50–70% of patients diagnosed with lung cancer suffer from COPD, and reduced lung ...
Abdel-Aziz +51 more
core +1 more source
Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease [PDF]
, 2016 Background: Cigarette smoke induced oxidative stress has been shown to reduce silent information regulator 1 (Sirt1) levels in lung tissue from smokers and patients with COPD patients.
Akai, Masaya +11 more
core +2 more sources
Progress in the mechanism and targeted drug therapy for COPD
Signal Transduction and Targeted Therapy, 2020 Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis characterised by long-term breathing problems and poor airflow. The prevalence of COPD has increased over the last decade and the drugs most commonly used to treat it ...
Cuixue Wang +6 more
semanticscholar +1 more source
Beta(2)-adrenergic receptor (ADRB2) gene polymorphisms and risk of COPD exacerbations : the Rotterdam study [PDF]
, 2019 The role of the beta(2)-adrenergic receptor (ADRB2) gene in patients with chronic obstructive pulmonary disease (COPD) is unclear. We investigated the association between ADRB2 variants and the risk of exacerbations in COPD patients treated with inhaled ...
Brusselle, Guy +8 more
core +2 more sources
Thorax, 2015 Dear Editor, We read with great interest the paper by Jones et al 1 about the prevalence, clinical correlates and response to pulmonary rehabilitation of sarcopenia in COPD. We believe that authors have meritoriously focused their attention on a highly relevant topic, which is the skeletal muscle decline in patients with COPD. Sarcopenia represents a
Matteo Cesari +3 more
openaire +3 more sources