Results 101 to 110 of about 28,140 (260)

COPII cage assembly factor Sec13 integrates information flow regulating endomembrane function in response to human variation

Scientific Reports
How information flow is coordinated for managing transit of 1/3 of the genome through endomembrane pathways by the coat complex II (COPII) system in response to human variation remains an enigma.
F. Anglès, Vijay Gupta, Chao Wang, William E. Balch   +3 more
semanticscholar   +1 more source

Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite

Traffic, Volume 27, Issue 1, March 2026.
This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light chain, and AP‐1 γ subunit were found associated with certain proteins known to be involved in cytostome function, and they were localized at the collars of ...
Jun Miao, Amuza Byaruhanga Lucky, Gang Ning, Xian Xia, Xiaoying Liang, Faiza Siddiqui, Hui Min, Chengqi Wang, Xiaolian Li, Z. Hong Zhou, Liwang Cui   +10 more
wiley   +1 more source

ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate

eLife, 2017
Native cargo proteins exit the endoplasmic reticulum (ER) in COPII-coated vesicles, whereas resident and misfolded proteins are substantially excluded from vesicles by a retention mechanism that remains unresolved.
Wenfu Ma, Elena Goldberg, Jonathan Goldberg   +2 more
doaj   +1 more source

TUMORI ADRENOTESTICULARE LA UN ADOLESCENT CU SINDROM ADRENOGENITAL – REZULTATE DUPĂ UN AN [PDF]

Romanian Journal of Pediatrics, 2012
Introducere. Sindromul adrenogenital este o boală genetică care are ca rezultat producţia scăzută de cortizol şi aldosteron. Pacienţii de sex masculin cu sindrom adrenogenital pot prezenta tumori adrenotesticulare. Scop.
Adela Chiriţă, Ramona Cojocaru, Monica Marazan, Corina Duncescu, Ramona Stroescu, Bogdana Zoica, Ioana Micle   +6 more
doaj   +1 more source

Membrane-coating lattice scaffolds in the nuclear pore and vesicle coats: Commonalities, differences, challenges [PDF]

, 2011
The nuclear pore complex (NPC) regulates all traffic between the cytoplasm and the nucleus. It is a large protein assembly composed of multiple copies of ~30 nucleoporins (nups).
Leksa, Nina Carolina, Schwartz, Thomas
core   +1 more source

RHBDL4-triggered downregulation of COPII adaptor protein TMED7 suppresses TLR4-mediated inflammatory signaling

Nature Communications
The toll-like receptor 4 (TLR4) is a central regulator of innate immunity that primarily recognizes bacterial lipopolysaccharide cell wall constituents to trigger cytokine secretion.
J. D. Knopf, Susanne S. Steigleder, Friederike Korn, Nathalie Kühnle, Marina Badenes, Marina Tauber, Sebastian J. Theobald, J. Rybniker, C. Adrain, Marius K. Lemberg   +9 more
semanticscholar   +1 more source

Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang, Pengfei Jiang, Joshua B Stein, Yannan Hou, Chaochen Zhou, Heemin Kang, Ki‐Bum Lee   +6 more
wiley   +1 more source

EVALUARE EPIDEMIOLOGICĂ ŞI PSIHO-SOCIALĂ A COPILULUI OBEZ – STUDIU PROSPECTIV [PDF]

Romanian Journal of Pediatrics, 2016
Obiectiv. Studiul de faţă şi-a propus evaluarea unor parametri epidemiologici şi psiho-sociali într-un eşantion de copii supraponderali şi obezi spitalizaţi pentru diverse patologii. Durata studiului a fost de 12 luni. Material şi metodă.
Oana Elena Iaru, Raluca Maria Vlad, Marina Popov, Roxana Andrei, Irina Dijmărescu, Daniela Păcurar, Dumitru Orăşeanu   +6 more
doaj   +1 more source

Molecular architecture of the Nup84–Nup145C–Sec13 edge element in the nuclear pore complex lattice [PDF]

, 2009
Nuclear pore complexes (NPCs) facilitate all nucleocytoplasmic transport. These massive protein assemblies are modular, with a stable structural scaffold supporting more dynamically attached components.
A Fotin, A Harel, AGW Leslie, AJ McCoy, AM Waterhouse, AT Brünger, BV Strokopytov, C Vonrhein, CS Bond, D Devos, D Devos, D Stoffler, E Dultz, E Fabre, E Krissinel, E Krissinel, E Onischenko, EJ Tran, EW Debler, F Alber, G Drin, G Rabut, GA Ratner, GM Sheldrick, HT McMahon, IC Berke, J Zimmerberg, JR Whittle, K Weis, KC Hsia, M Beck, M Kampmann, M Lutzmann, M Lutzmann, MA D'Angelo, MP Rout, MP Rout, N Elad, N Handa, N Schrader, NC Leksa, P Emsley, PD Adams, RC Edgar, S Fath, S Frey, S Jeudy, S Siniossoglou, SG Brohawn, SG Brohawn, SG Brohawn, SM Stagg, Stephen G Brohawn, T Boehmer, T Boehmer, T Makio, TC Walther, Thomas U Schwartz, TU Schwartz, V Galy, Y Jia, Y Shibata, Z Otwinowski   +62 more
core   +1 more source

Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast [PDF]

, 2018
The yeast Saccharomyces cerevisiae is widely used as a cell factory to produce recombinant proteins. However, S. cerevisiae naturally secretes only a few proteins, such as invertase and the mating alpha factor, and its secretory capacity is limited.
Bao, Jichen, Huang, Mingtao, Nielsen, Jens, Petranovic, Dina   +3 more
core   +4 more sources