Results 111 to 120 of about 28,053 (261)

Cargo crowding contributes to sorting stringency in COPII vesicles

Journal of Cell Biology, 2020
Combining correlative light and electron microscopy with yeast genetics and biochemistry, Gomez-Navarro, Melero, and colleagues show that cargo recruitment into a constrained COPII vesicle restricts bulk flow, thereby contributing to sorting stringency ...
Natalia Gomez-Navarro, Alejandro Melero, Xiaohan Li, J. Boulanger, W. Kukulski, E. Miller   +5 more
semanticscholar   +1 more source

Proteomic and Lipidomic Profiling of Immune Cell‐Derived Subpopulations of Extracellular Vesicles

PROTEOMICS, Volume 26, Issue 2-3, Page 129-153, February 2026.
ABSTRACT Extracellular vesicles (EVs) are heterogeneous and play important roles in intercellular communication, contributing to physiological and pathological processes. Since few markers currently exist to differentiate subtypes of EVs, this study aimed to determine proteomic and lipidomic differences among four EV subpopulations. Large and small EVs
Anna Lischnig, Nasibeh Karimi, Per Larsson, Karin Ekström, Rossella Crescitelli, Anna‐Carin Olin, Cecilia Lässer   +6 more
wiley   +1 more source

ER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate

eLife, 2017
Native cargo proteins exit the endoplasmic reticulum (ER) in COPII-coated vesicles, whereas resident and misfolded proteins are substantially excluded from vesicles by a retention mechanism that remains unresolved.
Wenfu Ma, Elena Goldberg, Jonathan Goldberg   +2 more
doaj   +1 more source

EVALUARE EPIDEMIOLOGICĂ ŞI PSIHO-SOCIALĂ A COPILULUI OBEZ – STUDIU PROSPECTIV [PDF]

Romanian Journal of Pediatrics, 2016
Obiectiv. Studiul de faţă şi-a propus evaluarea unor parametri epidemiologici şi psiho-sociali într-un eşantion de copii supraponderali şi obezi spitalizaţi pentru diverse patologii. Durata studiului a fost de 12 luni. Material şi metodă.
Oana Elena Iaru, Raluca Maria Vlad, Marina Popov, Roxana Andrei, Irina Dijmărescu, Daniela Păcurar, Dumitru Orăşeanu   +6 more
doaj   +1 more source

Molecular analysis and intestinal expression of SAR1 genes and proteins in Anderson's disease (Chylomicron retention disease). [PDF]

, 2011
International audienceBACKGROUND: Anderson's disease (AD) or chylomicron retention disease (CMRD) is a very rare hereditary lipid malabsorption syndrome.
Georges, Amandine, Bonneau, Jessica, Bonnefont-Rousselot, Dominique, Champigneulle, Jacqueline, Rabès, Jean, Abifadel, Marianne, Aparicio, Thomas, Guenedet, Jean, Bruckert, Eric, Boileau, Catherine, Morali, Alain, VARRET, Mathilde, Aggerbeck, Lawrence, Samson-Bouma, Marie   +13 more
core   +3 more sources

PSEUDOCHISTUL DE PANCREAS LA COPII

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2022
Pancreatic injuries include a variety of injuries from simple contusion to complete rupture of the duct and pancreatic head. Although pancreatic lesions are rare in children, the pancreatic pseudocyst is the most common posttraumatic cystic lesion of the pancreas and is a localized collection containing pancreatic juice and the peripancreatic necrotic ...
Hanganu, E., Munteanu, V., Măndrășescu, D., Lăptoiu, A.   +3 more
openaire   +2 more sources

Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials

Advanced Science, Volume 13, Issue 4, 19 January 2026.
Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang, Pengfei Jiang, Joshua B Stein, Yannan Hou, Chaochen Zhou, Heemin Kang, Ki‐Bum Lee   +6 more
wiley   +1 more source

SISTEMUL DE CLASIFICARE A FUNCŢIEI MOTORII GROSIERE ŞI SISTEMUL DE CLASIFICARE A ABILITĂŢII MANUALE ÎN EVALUAREA PARALIZIEI CEREBRALE [PDF]

Romanian Journal of Pediatrics, 2016
Paralizia cerebrală (PC) este o boală cerebrală cronică, definită ca un grup de afecţiuni motorii neprogresive care debutează în primul an de viaţă şi care sunt secundare leziunilor survenite la un creier aflat în dezvoltare.
Ioana Grigore, Georgeta Diaconu, Cătălin Prazaru, Alexandra Mania, Ana Ulinici   +4 more
doaj   +1 more source

Three-dimensional structure and flexibility of a membrane-coating module of the nuclear pore complex. [PDF]

, 2009
The nuclear pore complex mediates nucleocytoplasmic transport in all eukaryotes and is among the largest cellular assemblies of proteins, collectively known as nucleoporins. Nucleoporins are organized into distinct subcomplexes.
Blobel, Günter, Kampmann, Martin
core   +2 more sources

Proteomic Profiling of Mammalian COPII and COPI Vesicles.

Cell Reports, 2019
Intracellular transport and homeostasis of the endomembrane system in eukaryotic cells depend on the formation and fusion of vesicular carriers. Coat protein complex (COP) II vesicles export newly synthesized secretory proteins from the endoplasmic ...
Frank Adolf, M. Rhiel, Bernd Hessling, Qi Gao, A. Hellwig, J. Béthune, F. Wieland   +6 more
semanticscholar   +1 more source