The small GTPase Sar1, control centre of COPII trafficking
Sar1 is a small GTPase of the ARF family. Upon exchange of GDP for GTP, Sar1 associates with the endoplasmic reticulum (ER) membrane and recruits COPII components, orchestrating cargo concentration and membrane deformation.
Sander Van der Verren, Giulia Zanetti
semanticscholar +1 more source
NEUROBLASTOMUL CU DISEMINARE METASTATICĂ, PREZENTARE NEONATALĂ-CASE REPORT
Neuroblastoamele sunt tumori cu origine in celule sușe ale sistemului nervos simpatic, derivate din crestele neurale, reprezentând70% dintre tumorile cu localizare la nivelul glandei suprarenale.
Radu-Constantin LUCA +5 more
doaj +1 more source
Multi-scale Molecular Imaging of Human Cells reveals COPI and COPII Vesicles at ER Exit Sites
Downes K +5 more
europepmc +2 more sources
A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]
Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel +1 more
core +5 more sources
SEC31a-ATG9a Interaction Mediates the Recruitment of COPII Vesicles for Autophagosome Formation. [PDF]
Autophagy plays an important role in determining stem‐cell differentiation. During the osteogenic differentiation of mesenchymal stem cells (MSCs), autophagosome formation is upregulated but the reason is unknown.
Nie J +9 more
europepmc +2 more sources
The endoplasmic reticulum (ER) acts as the starting point of the secretory pathway, where approximately one-third of the proteins are correctly folded and modified, loaded into vesicles, and transported to the Golgi for further processing and ...
Huifang Qian +11 more
semanticscholar +1 more source
Atrezia de esofag – complicaţii gastrointestinale şi nutriţionale [PDF]
Atrezia de esofag (AE) este una dintre cele mai frecvente malformații de tub digestiv, fiind asociatǎ în 50% dintre cazuri cu alte malformații. Progresele tehnicilor chirurgicale și tratamentelor acordate în terapia intensivǎ neonatalǎ, alături de ...
Ioana-Valentina Nenciu +3 more
doaj +1 more source
Distinct stages in the recognition, sorting, and packaging of proTGFα into COPII-coated transport vesicles. [PDF]
In addition to its role in forming vesicles from the endoplasmic reticulum (ER), the coat protein complex II (COPII) is also responsible for selecting specific cargo proteins to be packaged into COPII transport vesicles.
Schekman, Randy, Zhang, Pengcheng
core +2 more sources
COLONIZAREA NAZOFARINGIANĂ CU STAFILOCOC AURIU LA NOU-NĂSCUT [PDF]
Staphylococcus aureus este un agent patogen important în perioada neonatală. Infecţiile stafi lococice sunt responsabile de o rată crescută a morbidităţii şi mortalităţii în rândul nou-născuţilor.
Oana Falup-Pecurariu +2 more
doaj +1 more source
COPII collar defines the boundary between ER and ER exit site and does not coat cargo containers
Live-cell microscopy reveals a novel mode of function for COPII: COPII binds the membrane at the boundary between the ER and ER exit sites, where it executes cargo sorting and concentration into ERES and does not coat cargo exporting containers.
Olga Shomron +18 more
semanticscholar +1 more source

