Results 31 to 40 of about 28,140 (260)
SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion. [PDF]
, 2013 The secretory pathway of eukaryotic cells packages cargo proteins into COPII-coated vesicles for transport from the endoplasmic reticulum (ER) to the Golgi.
Adams, Elizabeth +17 more
core +1 more source
COPII–Golgi protein interactions regulate COPII coat assembly and Golgi size [PDF]
The Journal of Cell Biology, 2006 Under experimental conditions, the Golgi apparatus can undergo de novo biogenesis from the endoplasmic reticulum (ER), involving a rapid phase of growth followed by a return to steady state, but the mechanisms that control growth are unknown. Quantification of coat protein complex (COP) II assembly revealed a dramatic up-regulation at exit sites driven
Guo, Yusong, Linstedt, Adam D.
openaire +3 more sources
CAPCANE DE DIAGNOSTIC ÎN PATOLOGIA CERVICALĂ A COPILULUI [PDF]
Romanian Journal of Pediatrics, 2011 Patologia cervicală la copil implică numeroase boli cu exprimare clinică asemănătoare. Autorii prezintă două cazuri de afectare laterocervicală non-oncologică la copil (boala zgârieturii de pisică şi malformaţie vasculară venoasă în relaţie cu vena ...
Alina Murgu +5 more
doaj +1 more source
KLHL12 can form large COPII structures in the absence of CUL3 neddylation
Molecular Biology of the Cell, 2023 CUL3-RING ubiquitin ligases (CRL3s) are involved in various cellular processes through different Bric-a-brac, Tramtrack, and Broad-complex (BTB)–domain proteins.
Tamara Moretti +3 more
semanticscholar +1 more source
Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]
, 2012 Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Hodgson, Lorna +3 more
core +2 more sources
Cryo-electron tomography reveals how COPII assembles on cargo-containing membranes. [PDF]
Nat Struct Mol BiolProteins traverse the eukaryotic secretory pathway through membrane trafficking between organelles. The COPII coat mediates the anterograde transport of newly synthesised proteins from the endoplasmic reticulum, engaging cargoes with a wide range of size
Pyle E, Miller EA, Zanetti G.
europepmc +2 more sources
Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]
, 2013 Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Crawford, Sue E. +4 more
core +2 more sources
ACUTE GASTROENTERITIS IN CHILDREN-THERAPEUTIC PRINCIPLES [PDF]
Romanian Journal of Pediatrics, 2008 This report presents updated recommendations for the optimal management of acute gastroenteritis in childhood, according to fundamental therapeutical principles recommended by ESPGHAN ( European Society of Paediatric Gastroenterology, Hepatology and ...
Victoria Hurduc +4 more
doaj +1 more source
Endoplasmic Reticulum Export of GPI-Anchored Proteins [PDF]
, 2019 Protein export from the endoplasmic reticulum (ER) is an essential process in all eukaryotes driven by the cytosolic coat complex COPII, which forms vesicles at ER exit sites for transport of correctly assembled secretory cargo to the Golgi apparatus ...
López Martín, Sergio +3 more
core +1 more source
Cell, 2007 Newly synthesized proteins en route to the Golgi apparatus are exported from the endoplasmic reticulum by COPII coated vesicles. Fath et al. (2007) now reveal the structure of a large portion of the yeast Sec13/31 complex, which comprises the coat framework of COPII-coated vesicles.
openaire +2 more sources