Results 21 to 30 of about 2,206,862 (377)

Cupric-polymeric nanoreactors integrate into copper metabolism to promote chronic diabetic wounds healing. [PDF]

Mater Today Bio
Tang Q, Tan Y, Leng S, Liu Q, Zhu L, Wang C.   +5 more
europepmc   +2 more sources

Transcriptome Analysis Uncovers a Link Between Copper Metabolism, and Both Fungal Fitness and Antifungal Sensitivity in the Opportunistic Yeast Candida albicans [PDF]

bioRxiv, 2020
Copper homeostasis is an important determinant for virulence of many human pathogenic fungi such as the highly prevalent yeast Candida albicans. However, beyond the copper transporter Ctr1, little is known regarding other genes and biological processes ...
Inès Khemiri, Faïza Tebbji, Adnane Sellam   +2 more
openalex   +2 more sources

Metabolism of copper and possibilities for its regulation [PDF]

Proceedings of the Estonian Academy of Sciences, 2023
Copper is an indispensable biometal participating as a redox catalyst in many important biochemical processes. However, if uncontrolled, copper ions induce the formation of reactive oxygen species and become toxic.
Peep Palumaa
doaj   +1 more source

Copper metabolism-related Genes in entorhinal cortex for Alzheimer's disease. [PDF]

Sci Rep, 2023
Zhang Y, Yang YS, Wang CM, Chen WC, Chen XL, Wu F, He HF.   +6 more
europepmc   +3 more sources

The Molecular Mechanisms of Defective Copper Metabolism in Diabetic Cardiomyopathy. [PDF]

Oxid Med Cell Longev, 2022
Copper is an essential trace metal element that significantly affects human physiology and pathology by regulating various important biological processes, including mitochondrial oxidative phosphorylation, connective tissue crosslinking, and antioxidant ...
Cui X, Wang Y, Liu H, Shi M, Wang J, Wang Y.   +5 more
europepmc   +2 more sources

Copper metabolism and its implications for canine nutrition. [PDF]

Transl Anim Sci
Canine copper nutrition has received increased attention due to recent reports of apparent copper-associated hepatitis in the USA and European Union. In order to properly address the need to modify the U.S.
Amundson LA, Kirn BN, Swensson EJ, Millican AA, Fahey GC.   +4 more
europepmc   +2 more sources

Analyzing Immune Cell Infiltration and Copper Metabolism in Diabetic Foot Ulcers. [PDF]

J Inflamm Res
Background Diabetes impairs wound healing, notably in diabetic foot ulcers (DFU). Stress, marked by the accumulation of lipoylated mitochondrial enzymes and the depletion of Fe–S cluster proteins, triggers cuproptosis—a distinct form of cell death.
Yi WJ, Yuan Y, Bao Q, Zhao Z, Ding HS, Song J.   +5 more
europepmc   +2 more sources

Development of a copper metabolism-related gene signature in lung adenocarcinoma. [PDF]

Front Immunol, 2022
Purpose The dysregulation of copper metabolism is closely related to the occurrence and progression of cancer. This study aims to investigate the prognostic value of copper metabolism-related genes (CMRGs) in lung adenocarcinoma (LUAD) and its ...
Chang W, Li H, Zhong L, Zhu T, Chang Z, Ou W, Wang S.   +6 more
europepmc   +2 more sources

Copper metabolism in osteoarthritis and its relation to oxidative stress and ferroptosis in chondrocytes. [PDF]

Front Mol Biosci
Ferroptosis, an iron-ion-dependent process of lipid peroxidation, damages the plasma membrane, leading to non-programmed cell death. Osteoarthritis (OA), a prevalent chronic degenerative joint disease among middle-aged and older adults, is characterized ...
Yu Q, Xiao Y, Guan M, Zhang X, Yu J, Han M, Li Z.   +6 more
europepmc   +2 more sources

Pan-cancer genetic analysis of cuproptosis and copper metabolism-related gene set

Frontiers in Oncology, 2022
Background A recent paper has revealed a novel cell death pathway, cuproptosis, a programmed cell death based on copper. This study aimed to evaluate the pan-cancer genomics and clinical association of cuproptosis and copper metabolism-related cell death
Hengrui Liu, Tao-Ming Tang
semanticscholar   +1 more source