Results 11 to 20 of about 112,456 (244)
Copper metabolism in hepatocellular carcinoma: from molecular mechanisms to therapeutic opportunities [PDF]
Frontiers in Molecular BiosciencesCopper is a vital trace metal that facilitates cell proliferation, angiogenesis, and tumour spread. The liver is essential for copper metabolism, hence regulating copper levels is crucial for hepatic health.
Ziling Pang
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HeliyonCopper, a vital trace element, orchestrates diverse cellular processes ranging from energy production to antioxidant defense and angiogenesis. Copper metabolism and cuproptosis are closely linked in the context of human diseases, with a particular focus ...
K.M. Abdullah +7 more
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The interplay between copper metabolism and microbes: in perspective of host copper-dependent ATPases ATP7A/B [PDF]
Frontiers in Cellular and Infection Microbiology, 2023 Copper, a vital element in various physiological processes, is transported from the gastrointestinal tract to tissues and cells through diverse copper transporters.
Yixuan Zhou +5 more
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α-Lipoic acid: a potential regulator of copper metabolism in Alzheimer’s disease [PDF]
Frontiers in Molecular BiosciencesAlzheimer’s disease (AD) is characterized by classic hallmarks such as amyloid plaques and neurofibrillary tangles, however, intensive research has broadened its scope to explore additional underlying mechanisms. Notably, disruptions in metal homeostasis,
Sigrid Kirss +5 more
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Identification of a copper metabolism‐related gene signature for predicting prognosis and immune response in glioma [PDF]
Cancer Medicine, 2023 Background Gliomas are highly refractory intracranial cancers characterized by genetic and transcriptional heterogeneity. However, therapeutic options are limited.
Ling Li +6 more
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The impact of copper on bone metabolism
Journal of Orthopaedic TranslationCopper is an essential trace element for the human body. Abnormalities in copper metabolism can lead to bone defects, mainly by directly affecting the viability of osteoblasts and osteoclasts and their bone remodeling function, or indirectly regulating ...
Zihan Zhang +3 more
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Disorders of Copper Metabolism in Children—A Problem too Rarely Recognized [PDF]
MetabolitesCopper plays an important role in metabolic processes. Both deficiency and excess of this element have a negative effect and lead to pathological conditions. Copper is a cofactor of many enzymatic reactions.
Sabina Więcek, Justyna Paprocka
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Metabolism of copper and possibilities for its regulation [PDF]
Proceedings of the Estonian Academy of Sciences, 2023 Copper is an indispensable biometal participating as a redox catalyst in many important biochemical processes. However, if uncontrolled, copper ions induce the formation of reactive oxygen species and become toxic.
Peep Palumaa
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The Copper Metabolism of Drosophila [PDF]
Proceedings of the National Academy of Sciences, 1952 Uploaded by Plazi for TaxoDros. We do not have abstracts.
D F, Poulson +3 more
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Lipid and energy metabolism in Wilson disease
Liver Research, 2020 Copper accumulation and deficiency are reciprocally connected to lipid metabolism. In Wilson disease (WD), which is caused by a genetic loss of function of the copper-transporting P-type ATPase beta, copper accumulates mainly in the liver and lipid ...
Tagreed A. Mazi +2 more
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