Results 31 to 40 of about 2,835,414 (282)

An algebra of deformation quantization for star-exponentials on complex symplectic manifolds [PDF]

open access: yes, 2006
The cotangent bundle $T^*X$ to a complex manifold $X$ is classically endowed with the sheaf of $\cor$-algebras $\W[T^*X]$ of deformation quantization, where $\cor\eqdot \W[\rmptt]$ is a subfield of $\C[[\hbar,\opb{\hbar}]$. Here, we construct a new sheaf
Giuseppe Dito   +7 more
core   +5 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Respostas correlacionadas do algodoeiro com a seleção para a coloração da fibra [PDF]

open access: yesPesquisa Agropecuária Brasileira, 2003
Os constantes trabalhos de melhoramento com o algodão de fibra branca produziram cultivares superiores com fibra de melhor qualidade tecnológica do que a do algodão de fibra colorida.
Luiz Paulo de Carvalho   +1 more
doaj   +1 more source

Toric plurisubharmonic functions and analytic adjoint ideal sheaves [PDF]

open access: yes, 2011
In the first part of this paper, we study the properties of some particular plurisubharmonic functions, namely the toric ones. The main result of this part is a precise description of their multiplier ideal sheaves, which generalizes the algebraic case ...
Guenancia, Henri
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Geo-Biological Investigations on Azooxanthellate Cold-Water Coral Reefs on the Carbonate Mounds Along the Celtic Continental Slope [PDF]

open access: yes, 2004
Northeast Atlantic 2004 Cruise No.
Bannert, Bernhard   +27 more
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Keep praying [PDF]

open access: yes, 2005
1 Cor 14 ...
Powell, Kevin
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

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