Results 81 to 90 of about 6,100 (143)

Therapy-induced remodeling of IgG and plasma N-glycans in breast cancer

BMC Cancer
Background Protein N-glycosylation plays a key role in cancer biology and may offer insights into tumor behavior and treatment response. This study investigated changes in N-glycosylation of immunoglobulin G (IgG) and total plasma proteins in patients ...
Martina Maričić Vrban, Barbara Radovani Trbojević, David Visentin, Katarina Ramljak, Iva Kirac, Mihaela Gaće, Ivan Milas, Gordan Lauc, Dragan Primorac, Ivan Gudelj   +9 more
doaj   +1 more source

A high-resolution N-glycoproteome landscape of aging mouse ovary

Redox Biology
Ovarian aging typically precedes the decline of other organ systems, yet its molecular mechanisms remain poorly understood. Glycosylation as one of the most important protein modifications has been especially unexplored in this context.
Yongqi Wu, Zhida Zhang, Yongchao Xu, Yingjie Zhang, Lin Chen, Yiwen Zhang, Ke Hou, Muyao Yang, Zhehui Jin, Yinli Cai, Jiayu Zhao, Shisheng Sun   +11 more
doaj   +1 more source

FUT8-Mediated Core Fucosylation Promotes the Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension. [PDF]

Aging Dis, 2023
Zhang W, Lin W, Zeng X, Zhang M, Chen Q, Tang Y, Sun J, Liang B, Zha L, Yu Z.   +9 more
europepmc   +1 more source

FUT8 reprograms glycolytic metabolism to promote PKM2 lactylation and drive clear cell renal cell carcinoma progression

Cell Death Discovery
Clear cell renal cell carcinoma (ccRCC) is characterized by the loss of the von Hippel–Lindau (VHL) gene, leading to constitutive activation of hypoxia-inducible transcription factors (HIFs) and metabolic reprogramming toward aerobic glycolysis. Although
Zikai Guo, Hongxiao Jiang, Xu Wang, Ke Xuan, Huidong Zhong, Chengxi Liu, Mengkai Zhang, Zhichao Li, Weiren Huang, Yangyang Sun   +9 more
doaj   +1 more source

Retracted: Glycyrrhizic Acid Inhibits Core Fucosylation Modification Modulated EMT and Attenuates Bleomycin-Induced Pulmonary Fibrosis. [PDF]

Evid Based Complement Alternat Med, 2023
And Alternative Medicine EC.
europepmc   +1 more source

Importance of core fucosylation in regulating neuroinflammation

Importance of core fucosylation in regulating neuroinflammation
令和5年度
openaire  

Functional analysis of core fucosylation in neuroinflammation

Functional analysis of core fucosylation in neuroinflammation
平成30年度
openaire  

Abstracts From AIDS 2026, the 26th International AIDS Conference, 26 – 31 July 2026 Rio de Janeiro, Brazil & virtual

Journal of the International AIDS Society, Volume 29, Issue S4, July 2026.
wiley   +1 more source

The role of FUT8-catalyzed core fucosylation in Alzheimer's amyloid-β oligomer-induced activation of human microglia. [PDF]

Glia, 2023
Jin LW, di Lucente J, Ruiz Mendiola U, Tang X, Zivkovic AM, Lebrilla CB, Maezawa I.   +6 more
europepmc   +1 more source

Anastrozole and Tamoxifen Impact on IgG Glycome Composition Dynamics in Luminal A and Luminal B Breast Cancers

Antibodies
This study examines the intricate relationship between protein glycosylation dynamics and therapeutic responses in Luminal A and Luminal B breast cancer subtypes, focusing on anastrozole and tamoxifen impacts. The present methods inadequately monitor and
Borna Rapčan, Matko Fančović, Tea Pribić, Iva Kirac, Mihaela Gaće, Frano Vučković, Gordan Lauc   +6 more
doaj   +1 more source