Nonlinear Optical Corneal Crosslinking, Mechanical Stiffening, and Corneal Flattening Using Amplified Femtosecond Pulses. [PDF]
Purpose:We have shown that nonlinear optical corneal crosslinking (NLO CXL) and stiffening can be achieved in ex vivo rabbit corneas using an 80-MHz, 760-nm femtosecond (FS) laser, however the required power was beyond the American National Standard ...
Bradford, Samantha +6 more
core
The mechanical properties of amniotic membrane influence its effect as a biomaterial for ocular surface repair [PDF]
The human amniotic membrane (AM) is a tissue of fetal origin and has proven to be clinically useful as a biomaterial in the management of various ocular surface disorders including corneal stem cell transplantation. However, its success rate displays a
Alcock, Simon +6 more
core +1 more source
The article discusses the effectiveness of accelerated collagen crosslinking in the treatment of patients with corneal diseases, a common basic pathogenetic link of which is endothelial corneal decompensation.
S. Yu. Astakhov +3 more
doaj +1 more source
Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro +6 more
wiley +1 more source
Corneal biomechanical properties in different ocular conditions and new measurement techniques [PDF]
Several refractive and therapeutic treatments as well as several ocular or systemic diseases might induce changes in the mechanical resistance of the cornea.
Borges, José Salgado +5 more
core +3 more sources
Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma.
PurposeTo determine the effect of Ultraviolet-A collagen cross-linking with hypo-osmolar and iso-osmolar riboflavin solutions on stromal collagen ultrastructure in normal and keratoconus ex vivo human corneas.MethodsUsing small-angle X-ray scattering ...
Sally Hayes +12 more
doaj +1 more source
Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun +8 more
wiley +1 more source
An Overview of Tissue Engineering as an Alternative for Toxicity Assessment [PDF]
Tissue engineering is a multidisciplinary field that combines aspects of biology, material sciences, engineering and medicine - the ultimate goal being able to fabricate replacement tissues and/or organs for an ageing population.
Chau, David Y.S., Garrod, Mathew
core +1 more source
Corneal collagen cross-linking in patients with keratoconus associated with dry eye
Purpose The aim of this study was to assess the safety and efficacy of corneal collagen cross-linking in keratoconus associated with dry eye. Patients and methods This study included 35 eyes of 29 patients diagnosed as having keratoconus associated with ...
Tamer H El-Sersy
doaj +1 more source
Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu +6 more
wiley +1 more source

