Results 101 to 110 of about 959,050 (193)

Multi‐Omics Reveals STAT1 as a Central Regulator of Oxidative Stress‐Induced Senescence in the Aging Retina

Aging Cell, Volume 25, Issue 11, November 2026.
Integrated multi‐omics identifies STAT1 as a central regulator of retinal aging, linking oxidative stress, inflammation, and senescence at neuro‐glial interfaces. ABSTRACT Aging is the dominant risk factor for retinal neurodegeneration, yet the upstream regulators that coordinate senescence‐associated programs across retinal cell types remain ...
Yiran Fan, Ying Li, Xueying Wu, Lin Cai, Ruotong Yang, Zhenhui Liu, Yan Li, Bingtao Hao, Bo Lei, Xiuxiu Jin   +9 more
wiley   +1 more source

High Doses of N‐Acetyl‐P‐Aminophenol Cause Acute Changes in Electroencephalographic and Electrocardiographic Activities in Wistar Rats

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT N‐acetyl‐p‐aminophenol (APAP), or acetaminophen, is the most prescribed analgesic and antipyretic, even used in association with other drugs. Because it is easily bought in drugstores, much evidence about its toxic effects is known due to high doses or continuous use, which can lead to death in cases of intoxication.
Alex Luiz Menezes da Silva, Luiz Gustavo dos Reis de Freitas, Akira Otake Hamoy, Clarissa Araujo da Paz, Luan Oliveira Ferreira, Esther Padilha da Silveira, Maria Klara Otake Hamoy, Nilton Akio Muto, Dielly Catrina Favacho Lopes, Moisés Hamoy   +9 more
wiley   +1 more source

Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review

Clinical &Experimental Ophthalmology, Volume 54, Issue 8, Page 1054-1072, November 2026.
ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu, Yajuan Zheng, Mingxuan Wang, Jing Zhao   +3 more
wiley   +1 more source

Pigmented corneal striae: An overlooked clinical sign associated with equine anterior uveal melanocytic neoplasia

Equine Veterinary Education, EarlyView.
R. J. McMullen Jr
wiley   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9809-9818, November 2026.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Limbal cystotomy by fine needle aspiration of a translucent iris cyst in a horse

Equine Veterinary Education, Volume 38, Issue 11, Page e784-e789, November 2026.
Summary A 4‐year‐old Cremello crossbred mare was referred to the Equine Veterinary Teaching Hospital of Utrecht University for a translucent iris cyst from the dorsal pupillary margin corpora nigra in the right eye. Although noninvasive diode laser treatment is the preferred method of pigmented cyst ablation, two attempts did not result in disruption ...
A. L. Hendrikx, S. Veraa, J. P. A. M. van Loon, H. Hermans, I. J. M. Slenter, E. M. S. Visser   +5 more
wiley   +1 more source

Molecular mechanisms and modulation of Endothelial Progenitor Cell function in South Asian men [PDF]

, 2012
South Asian ethnicity has long been considered a contributory factor in the development of atherosclerosis and cardiovascular disease. Endothelial dysfunction is considered to be the precursor of atherosclerosis, and South Asian ethnicity has been linked
Baliga, Vivek
core   +2 more sources

Corneal Xenotransplantation: Lessons From Allograft Immunobiology and Emerging Translational Strategies

Xenotransplantation, Volume 33, Issue 6, November/December 2026.
ABSTRACT Corneal transplantation is an effective sight‐restoring procedure, yet its global impact remains constrained by limited and uneven access to human donor tissue and by immune‐mediated graft failure, particularly in high‐risk recipients. Xenotransplantation offers a potentially scalable alternative, but successful clinical translation requires ...
Ansu A. John, Ellen H. Koo
wiley   +1 more source

Endothelial Exostosin‐1 Is Needed for Glycocalyx Integrity and Inflammatory Resolution in Acute Lung Injury

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
Endothelial Ext1 is essential for maintaining heparan sulfate–rich endothelial glycocalyx integrity. Loss of Ext1 reduces glycocalyx thickness, resulting in enhanced leukocyte adhesion, increased vascular permeability, and exaggerated inflammatory responses following lipopolysaccharide (LPS) challenge.
Yuki Kawasaki, Hiroyuki Tomita, Kodai Suzuki, Chihiro Takada, Hirotaka Asano, Soichiro Kano, Yugo Wakayama, Hirotsugu Fukuda, Toru Minamiyama, Genki Yoshimura, Ryo Kamidani, Yoshinori Kakino, Tomotaka Miura, Yuichiro Kitagawa, Tetsuya Fukuta, Takahito Miyake, Akio Suzuki, Kazu Matsumoto, Nobuyuki Tetsuka, Shozo Yoshida, Yoichi Maekawa, Yu Yamaguchi, Hideshi Okada   +22 more
wiley   +1 more source

Post-phacoemulsification Corneal Edema: Pathophysiology, Risk Stratification, and Contemporary Management

Delhi Journal of Ophthalmology
Post-phacoemulsification corneal edema is a common postoperative complication and an important cause of delayed visual recovery after cataract surgery.
Aniket Laxmikant Ramteke, Kalaimani Senguttuven, Chavi Harkawat, Akshaya Balaji, Dewang Angmo   +4 more
doaj   +1 more source