Results 81 to 90 of about 959,050 (193)

Emerging Approaches for Phytoconstituent Delivery in the Management of Rheumatoid Arthritis: Bridging Nature and Nanotechnology

Phytotherapy Research, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is an autoimmune condition marked by joint inflammation, cartilage destruction, and bone damage. Conventional treatments, including NSAIDs and DMARDs, have shown effectiveness in slowing down disease progression, but prolonged exposure to such medications results in adverse effects and lack of tolerance among patients.
Yogesh Khairnar, Sakshi Priya, Madhavi Rajpara, Venkatesh K. P. Rao, Geeta Bhatt, Gautam Singhvi   +5 more
wiley   +1 more source

Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress [PDF]

, 2009
Oxidative stress plays an important role in the progression of vascular endothelial dysfunction. The two major systems generating vascular oxidative stress are the NADPH oxidase and the xanthine oxidase pathways. Allopurinol, a xanthine oxidase inhibitor,
Struthers, Allan D., Jacob George, George, Jacob   +2 more
core   +1 more source

Table_1_Extracellular Vesicles Derived From Human Corneal Endothelial Cells Inhibit Proliferation of Human Corneal Endothelial Cells.docx

, 2022
Corneal endothelial cells (CEnCs) are a monolayer of hexagonal cells that are responsible for maintaining the function and transparency of the cornea. Damage or dysfunction of CEnCs could lead to blindness.
Mohit Parekh (6643547), Sajjad Ahmad (768814), Hefin Rhys (9551069), Tiago Ramos (817043), Stefano Ferrari (224700)   +4 more
core   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

Comparative study of corneal endothelial morphology and central corneal thickness in diabetic and non-diabetic patients at tertiary care centre

BMC Ophthalmology
Background Diabetes mellitus is a chronic condition that affects various organs, including the eyes. Corneal endothelial dysfunction, a key factor in ocular health, can be influenced by long-term diabetes.
Surbhi Sharma, Veshal Vinod Madan, Susmita Banerjee   +2 more
doaj   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Optic nerve head blood flow autoregulation during isometric exercise in primary open‐angle glaucoma assessed by laser speckle flowgraphy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess optic nerve head blood flow (ONHBF) autoregulation in patients with early‐ to moderate‐stage primary open‐angle glaucoma (POAG) and age‐ and sex‐matched healthy controls using laser speckle flowgraphy (LSFG) and isometric handgrip exercise.
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Liudmyla Petric, Ulrich Graf, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

SLC4A11 depletion impairs NRF2 mediated antioxidant signaling and increases reactive oxygen species in human corneal endothelial cells during oxidative stress

Scientific Reports, 2017
Corneal endothelial dystrophy is a progressive disease with gradual loss of vision and characterized by degeneration and dysfunction of corneal endothelial cells.
Sanjukta Guha, Sunita Chaurasia, Charanya Ramachandran, Sanhita Roy   +3 more
doaj   +1 more source

Normal corneal endothelial cell density in Nigerians

, 2016
Temitope Ewete,1 Efeoghene Uchenna Ani,2 Adegboyega Sunday Alabi1 1MeCure Eye Center, Lagos, 2Department of Ophthalmology, University of Port Harcourt, Port Harcourt, Nigeria Aim: The aim of the study was to describe the corneal endothelial cell ...
Ewete T, Ani EU, Alabi AS
core  

Inflammation and endothelial dysfunction with aging

, 2010
Aging is an independent risk factor for cardiovascular disease that is associated with chronic inflammation. The turnover of the endothelial layer is accelerated in aged subjects and endothelial dysfunction is observed after regeneration.
Vanhoutte, PMGR, Lee, MYK
core   +1 more source