Results 1 to 10 of about 35,735 (187)
Research Progress of Polymer Biomaterials as Scaffolds for Corneal Endothelium Tissue Engineering [PDF]
Nanomaterials, 2023 Nowadays, treating corneal diseases arising from injury to the corneal endothelium necessitates donor tissue, but these corneas are extremely scarce. As a result, researchers are dedicating significant efforts to exploring alternative approaches that do ...
Xiaoying Luo +8 more
doaj +2 more sources
Spatiotemporal gene targeting in the mouse corneal endothelium [PDF]
Taiwan Journal of Ophthalmology, 2023 PURPOSE: The inducible Cre-ERT2 recombinase system allows for temporal control of gene targeting, and it is useful to studying adult function of genes that have critical developmental roles.
JeongGoo Lee, Martin Heur
doaj +2 more sources
Nanoneedles Induce Targeted siRNA Silencing of p16 in the Human Corneal Endothelium [PDF]
Advanced Science, 2022 Nanoneedles can target nucleic acid transfection to primary cells at tissue interfaces with high efficiency and minimal perturbation. The corneal endothelium is an ideal target for nanoneedle‐mediated RNA interference therapy aimed at enhancing its ...
Eleonora Maurizi +7 more
doaj +2 more sources
The Multifarious Effects of Various Glaucoma Pharmacotherapy on Corneal Endothelium: A Narrative Review [PDF]
Ophthalmology and Therapy, 2023 Corneal endothelium is a single cell layer that is mainly responsible for maintaining corneal clarity. Endothelial damage secondary to toxicity, stress, or genetic predisposition are common and in conjunction with the low regenerative ability of the ...
Stylianos A. Kandarakis +6 more
doaj +2 more sources
Tissue engineered corneal endothelium transplantation in an ex vivo human cornea organ culture model [PDF]
Scientific ReportsTransplantation of corneal tissue is the standard treatment for irreversible corneal endothelium decompensation by replacing the malfunctioning corneal endothelial cells and Descemet’s membrane.
Meng-Chen Tsai +2 more
doaj +2 more sources
Diseases of the corneal endothelium. [PDF]
Exp Eye Res, 2021 The corneal endothelial monolayer and associated Descemet's membrane (DM) complex is a unique structure that plays an essential role in corneal function. Endothelial cells are neural crest derived cells that rest on a special extracellular matrix and play a major role in maintaining stromal hydration within a narrow physiologic range necessary for ...
Jeang LJ, Margo CE, Espana EM.
europepmc +3 more sources
Human Bone Derived Collagen for the Development of an Artificial Corneal Endothelial Graft. In Vivo Results in a Rabbit Model. [PDF]
PLoS ONE, 2016 Corneal keratoplasty (penetrating or lamellar) using cadaveric human tissue, is nowadays the main treatment for corneal endotelial dysfunctions. However, there is a worldwide shortage of donor corneas available for transplantation and about 53% of the ...
Natalia Vázquez +9 more
doaj +5 more sources
Ciência Rural, 2021 : The objective of this study was to evaluate the acute effects of ropivacaine hydrochloride on the corneal endothelium of horses. Forty-eight eyes were obtained from a commercial slaughterhouse and were randomly divided into three groups.
Marcele de Souza Muccillo +6 more
doaj +1 more source
Eye, 1990 The endothelium is a monolayer of cells on the posterior corneal surface that transports water from the stroma into the anterior chamber. This movement of water counters a natural tendency for the stroma to swell and is necessary to maintain a transparent cornea.
S J, Tuft, D J, Coster
openaire +2 more sources
PLoS ONE, 2021 Expansion of CTG trinucleotide repeats (TNR) in the transcription factor 4 (TCF4) gene is highly associated with Fuchs Endothelial Corneal Dystrophy (FECD).
Eric D Wieben +7 more
doaj +1 more source