Differentiation of Human Embryonic Stem Cells into Cells with Corneal Keratocyte Phenotype [PDF]
, 2013 Corneal transparency depends on a unique extracellular matrix secreted by stromal keratocytes, mesenchymal cells of neural crest lineage. Derivation of keratocytes from human embryonic stem (hES) cells could elucidate the keratocyte developmental pathway
Chan, AA +8 more
core +12 more sources
Feasibility of cell-based therapy combined with descemetorhexis for treating Fuchs endothelial corneal dystrophy in rabbit model. [PDF]
PLoS ONE, 2018 Corneal transparency is maintained by the corneal endothelium through its pump and barrier function. Severe corneal endothelial damage results in dysregulation of water flow and eventually causes corneal haziness and deterioration of visual function.
Naoki Okumura +10 more
doaj +1 more source
Recovery of Corneal Endothelial Cells from Periphery after Injury. [PDF]
PLoS ONE, 2015 Wound healing of the endothelium occurs through cell enlargement and migration. However, the peripheral corneal endothelium may act as a cell resource for the recovery of corneal endothelium in endothelial injury.To investigate the recovery process of ...
Sang Ouk Choi +7 more
doaj +1 more source
Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction. [PDF]
PLoS ONE, 2016 The corneal endothelium maintains corneal transparency by its pump and barrier functions; consequently, its decompensation due to any pathological reason causes severe vision loss due to corneal haziness.
Naoki Okumura +8 more
doaj +1 more source
Evaluation of equine corneal endothelium after exposure to 0.05% brilliant blue - an in vitro study [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2019 The aim of this study was to evaluate the immediate effects of 0.05% brilliant blue on corneal endothelium of horses. Thirty-eight corneas of 19 horses, male or female, of different ages were studied. Corneas were randomly divided into two groups.
M.C.C. Andrade +4 more
doaj +1 more source
Corneal endothelial regeneration in human eyes using endothelium-free grafts
BMC Ophthalmology, 2022 Background To report on corneal endothelial regeneration, graft clarity, and vision recovery when using endothelium-free grafts. Methods We evaluated the donor’s cell viability using trypan blue staining and dual staining with calcein acetoxy methyl ...
Lu-Yi Ying +5 more
doaj +1 more source
Long-Term Results after DMEK (Descemet’s Membrane Endothelial Keratoplasty) [PDF]
, 2020 Ziel der Arbeit: Evaluation der langfristigen Ergebnisse sowie der Komplikationsrate nach Descemet’s Membran Endothelialen Keratoplastik (DMEK) Methoden: Eine cross-sectional, Fall-Serien Studie.
Wardeh, Rima
core +1 more source
Specular microscopy of the corneal endothelial cells of bovines: An ex vivo study
Open Veterinary Journal, 2023 Background: The endothelium is the most posterior layer of the cornea and essential for maintaining corneal transparency. Due to variations in corneal endothelial parameters among different species, knowledge of the normal parameters for each species is
Mariane Gallicchio Azevedo +6 more
doaj +1 more source
Journal of Functional Biomaterials, 2015 Corneal endothelium is a single layer of specialized cells that lines the posterior surface of cornea and maintains corneal hydration and corneal transparency essential for vision.
Jesintha Navaratnam +3 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2022 Objective: To evaluate changes in corneal endothelium in patients with anterior uveitis by using specular microscopy and compare it with the corneal endothelium of healthy subjects. Study Design: Comparative cross-sectional study.
Qurat ul Ain Ghazanfar +3 more
doaj +1 more source