Results 71 to 80 of about 132,571 (292)

Salient features of the coronary collateral circulation and its clinical relevance

Swiss Medical Weekly, 2015
The coronary collateral circulation provides an alternative source of blood supply to myocardium jeopardised by ischaemia. Collaterals enlarge with obstructive coronary artery disease to allow bulk flow, but blood flow deliverable by the native, pre ...
Michael Stoller, Christian Seiler
doaj   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

An anatomically detailed arterial-venous network model. Cerebral and coronary circulation. [PDF]

Front Physiol, 2023
Müller LO, Watanabe SM, Toro EF, Feijóo RA, Blanco PJ.   +4 more
europepmc   +1 more source

Dual‐Energy CT‐Based Assessment of Thrombotic Heterogeneity for Predicting Stroke Source and Response to Machine Thrombectomy: A Step Toward Visualization Thrombus Treatment

Advanced Science, EarlyView.
The research indicates that dual energy CT scanning can accurately predict the stroke source and clinical outcomes by analyzing thrombus heterogeneity. Based on histopathological analysis of thrombus components, these scans are better able to display thrombus details than standard CT scans, which is helpful for the development of visual navigation ...
Jingxuan Jiang, Sijia Wang, Fan Xiao, Hongmei Gu, Mingkang Wang, Hao Tian, Baohui Guan, Kai Sheng, Yijia Xiong, Huilin Zhao, Minda Li, Li Xu, Zheng Sun, Haiyan Du, Wenxian Du, Yuehua Li   +15 more
wiley   +1 more source

UNDERNUTRITION IN THE TREATMENT OF CORONARY ARTERY DISEASE (PARTICULARLY THROMBOSIS). EFFECT ON THE BASAL METABOLISM AND CIRCULATION 1 [PDF]

, 1936
Arthur M. Mastér, Harry L. Jaffe, Simon Dack   +2 more
openalex   +1 more source

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Social isolation and loneliness with risk of cardiometabolic multimorbidity: A prospective cohort study from UK Biobank

iScience
Summary: The pandemic of the coronavirus disease 2019 resulted in an increased prevalence of social isolation and loneliness. Cox proportional hazards regression was used to test the association between social isolation/loneliness, multiple ...
Zhilin Xiao, Jing Li, Yi Luo, Liu Yang, Guogang Zhang, Xunjie Cheng, Yongping Bai   +6 more
doaj  

Factors Controlling the Coronary Circulation [PDF]

, 1946
L. N. Katz, W. Wise, K. Jochim
openalex   +1 more source

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

Advanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge, Shuying Wang, Zhaokai Li, Jing Yu, Binbin Liu, Ruiying Wang, Shichen Bu, Nawsher wan, Yan Wang, Cuilian Dai, Yijun Lin   +10 more
wiley   +1 more source

Pushing the Frontiers: Artificial Intelligence (AI)‐Guided Programmable Concepts in Binary Self‐Assembly of Colloidal Nanoparticles

Advanced Science, EarlyView.
Colloidal nanoparticles self‐assembly advances towards intelligent, customized assembly through precise control of binary co‐assemblies. This review explores the evolution from monolithic to binary assemblies, highlighting how the AI‐guided programmable assembly approach has the potential to shift from passive assembly to active intelligent design.
Cancan Li, Lindong Ma, Zhenjie Xue, Xiao Li, Shan Zhu, Tie Wang   +5 more
wiley   +1 more source