Results 91 to 100 of about 1,009,765 (207)

ANK1 and EPB41 Variants and The Risk of Glucocorticoid‐Induced Osteonecrosis

Arthritis &Rheumatology, Volume 78, Issue 11, Page 2378-2389, November 2026.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

Exercise‐Based Management of Diabetic Cardiomyopathy: Preclinical Mechanisms, Clinical Evidence, and Translational Strategies

Journal of Diabetes, Volume 18, Issue 11, November 2026.
Exercise may mitigate diabetic cardiomyopathy by improving mitochondrial metabolism, redox balance, calcium handling, and inflammatory‐fibrotic remodeling. Translation into clinical practice requires phenotype‐ and risk‐adapted exercise prescriptions, standardized dose reporting, and multimodal monitoring to define safety, efficacy, and long‐term ...
Xiaoya Li, Zhiqiang Wang, Jingjing Liu
wiley   +1 more source

Coronary Microcirculation: The Next Frontier in the Management of STEMI

, 2023
Although the widespread adoption of timely invasive reperfusion strategies over the last two decades has significantly improved the prognosis of patients with ST-segment elevation myocardial infarction (STEMI), up to half of patients after ...
Vladan Vukcevic, Vladimir Dedovic, Olga Nedeljkovic, Milorad Zivkovic, Dragana Sobic-Saranovic, Milika Asanin, Vladimir Zobenica, Dejan Milasinovic, Sanja Stankovic, Ruzica Maksimovic, Djordje Dukic, Dario Jelic, Zobenica, Vladimir, Maksimovic, Ruzica, Asanin, Milika, Vukcevic, Vladan, Stankovic, Sanja, Milasinovic, Dejan, Sobic-Saranovic, Dragana, Dukic, Djordje, Jelic, Dario, Nedeljkovic, Olga, Dedovic, Vladimir, Zivkovic, Milorad   +23 more
core   +1 more source

Association between insulin resistance and coronary microcirculatory function and adverse cardiovascular events after PCI in non-diabetic STEMI patients

Frontiers in Cardiovascular Medicine
ObjectiveHyperglycemia and insulin resistance (IR) are common in patients with acute ST-segment elevation myocardial infarction (STEMI). However, the impact of IR on coronary microcirculatory function in non-diabetic STEMI patients remains unclear.
Jinrong Zhong, Liming Tang, Yuanfeng Zhang   +2 more
doaj   +1 more source

15O‐water PET‐detected myocardial ischaemia and CT‐derived FFR: Predicting the functional significance of anatomical stenosis

Clinical Physiology and Functional Imaging, Volume 46, Issue 6, November 2026.
Abstract Aims Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. While coronary computed tomography angiography (CCTA) provides anatomical assessment of coronary stenoses, its ability to determine their functional significance is limited. Computed tomography‐derived fractional flow reserve (CT‐FFR) has emerged as a non‐
Vornanen J, Okkonen M, Ronkainen A‐P, Laitinen Tm, Laitinen Tp, Hedman M   +5 more
wiley   +1 more source

Coronary microcirculatory dysfunction after percutaneous coronary intervention: pathogenesis, diagnosis, and therapeutic strategies

Frontiers in Cardiovascular Medicine
Coronary microvascular dysfunction (CMD) can lead to a variety of severe adverse cardiovascular events. CMD represents the primary cause of recurrent angina pectoris following percutaneous coronary intervention (PCI).
Jin BoYuan, Wang TingTing, Hua ChengJun, Han XinYi, Chen YuShan   +4 more
doaj   +1 more source

Association of Lipid Ratios With Cardiovascular Outcomes in Type 2 Diabetes: A Population Cohort Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10236-10247, November 2026.
ABSTRACT Aims To identify low‐ and high‐risk intervals for major adverse cardiovascular events (MACE) and all‐cause mortality according to lipid ratios in adults with Type 2 diabetes mellitus (T2DM), stratified by sex. Materials and Methods We used primary care electronic health records from the Spanish National Health Service including 303 199 adults ...
Enrique Carretero‐Anibarro, Jose Antonio Quesada, Manuel A. Ruiz‐Quintero, Didac Mauricio, Kamlesh Khunti, Domingo Orozco‐Beltrán   +5 more
wiley   +1 more source

Prognostic Value and Population Attributable Fraction of Cardio‐Ankle Vascular Index for Mortality in the General Population

Geriatrics &Gerontology International, Volume 26, Issue 11, November 2026.
This 12.7‐year prospective study of 5,994 adults evaluated the cardio‐ankle vascular index (CAVI) as a mortality predictor. Compared to normal CAVI (< 8.0), elevated CAVI (≥ 9.0) significantly increased the risk for all‐cause mortality (HR: 1.38; PAF: 8.9%).
Shiroh Tanoue, Inria A. Zahra, Athira Nandakumar, Rie Ibusuki, Kazuyo Kuwabara, Ippei Shimoshikiryo, Rika Matsuyama, Saekhol Bakri, Alya Nisrina Fadhila, Toshiro Takezaki, Chihaya Koriyama   +10 more
wiley   +1 more source

The Role of Circulating Biomarkers in Patients with Coronary Microvascular Disease

Biomolecules
Coronary microvascular disease (CMD) comprises a spectrum of conditions characterized by the functional and structural abnormalities of coronary microcirculation, affecting vessels typically smaller than 500 μm.
Rossella Quarta, Giovanni Martino, Letizia Rosa Romano, Giovanni Lopes, Francesco Fabio Greco, Carmen Anna Maria Spaccarotella, Ciro Indolfi, Antonio Curcio, Alberto Polimeni   +8 more
doaj   +1 more source

Influence of age on the development of stress hyperglycemia during first‐onset ST‐elevation myocardial infarction

Journal of Diabetes Investigation, Volume 17, Issue 11, Page 1997-2008, November 2026.
Among 8,779 non‐diabetic patients with first‐onset STEMI, older age was associated with a higher likelihood of stress hyperglycemia. However, the excess mortality risk associated with stress hyperglycemia was greatest in younger patients and attenuated with advancing age, highlighting the possibility of age‐dependent prognostic significance.
Hon Jen Wong, Joy Xin Yi Au, Yao Hao Teo, Yao Neng Teo, Chen Ee Low, Chun En Yau, Norman H.Y. Lin, Pei Chia Eng, Li Feng Tan, Reshma A. Merchant, Ping Chai, Anand Adinath Ambhore, James W. L. Yip, Andrew Fu‐Wah Ho, David Foo, Pow‐Li Chia, Patrick Zhan‐Yun Lim, Khung Keong Yeo, Weien Chow, Daniel Thuan Tee Chong, Derek J. Hausenloy, Mark Y. Y. Chan, Ching‐Hui Sia   +22 more
wiley   +1 more source