Results 71 to 80 of about 1,009,765 (207)

Coronary microvascular dysfunction: an update

, 2013
Many patients undergoing coronary angiography because of chest pain syndromes, believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries, are found to have normal angiograms. In the past two decades, a number of studies
Crea, Filippo
core   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

Phytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia, Kaiyi Wu, Jiaying Qi, Nana Huang, Yusheng Liu, Xiumei Gao, Rong Sun   +6 more
wiley   +1 more source

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

Small, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan, Bei Song, Chengyun Liu, Peiyu Zhong, Quan Zhou, Xiaofang Zhao, Guangyu Gao, Xinyue Zhang, Xueke Guang, Tianci Yao, Ting Liu, Hao Zhang, Xinqi Diao, Weilin Lu   +13 more
wiley   +1 more source

Impaired Coronary Microcirculation and Myocardial Systolic Function: A Narrative Review on Non-Invasive Assessment in Cardiovascular Diseases

Life
Coronary microvascular dysfunction (CMD) is presently recognized as a condition characterized by a reduction in coronary blood flow. CMD is associated with poor cardiac outcomes, and mounting evidence suggests that coronary microcirculation may be ...
Evangelos Tatsis, Constantinos Papadopoulos, Dimitrios Oikonomidis, Lampros Lakkas, Katerina K. Naka   +4 more
doaj   +1 more source

Renal oxygenation, function and histopathology in an ovine model of heart failure undergoing cardiopulmonary bypass with 48 hours of recovery: a prospective, observational study*

Anaesthesia, EarlyView.
Summary Introduction Acute kidney injury is common after cardiac surgery requiring cardiopulmonary bypass, yet preventive strategies are limited. Progress has been hindered by a lack of clinically relevant experimental models incorporating pre‐existing heart disease.
Anton L. Trask‐Marino, Bruno Marino, Taku Furukawa, Lachlan F. Miles, Jai Raman, Andrew D. Cochrane, Peter R. McCall, Terase F. Lancefield, Roger G. Evans, Ian E. Birchall, Alemayehu H. Jufar, Ashenafi Betrie, Lars I.P. Snel, Munenori Kusunoki, Sally G. Hood, Linda Cornthwaite, Bruce Treagus, Connie Pei Chen Ow, Lindsea C. Booth, Clive N. May, Yugeesh R. Lankadeva   +20 more
wiley   +1 more source

The Coronary Microcirculation in Hamster-to-Rat Cardiac Xenografts [PDF]

, 2015
BACKGROUND The aim of this study was to establish a new experimental model to directly analyse the coronary microcirculation in cardiac xenografts. METHODS Intravital fluorescence microscopy (IVM) of the subepicardial microcirculation in heterotopically ...
Geiger, Dominik, Hagl, Christian, Michel, Sebastian, Reiche, Christoph A., Brenner, Paolo, Abicht, Jan, Reichart, Bruno, Schramm, René, Buchholz, Stefan   +8 more
core   +1 more source

Pathophysiology of coronary microcirculation dysfunction

Bulletin of the Academy of Sciences of Moldova. Medical Sciences
Coronary microcirculation dysfunction (CMD) comprises functional and structural alterations that impede blood flow through the arteriolarcapillary network of the heart. Three pathophysiological patterns have been recognised: (1) impaired microvascular vasodilation, (2) enhanced vasoconstrictor tone, and (3) diffuse microthrombosis.
openaire   +1 more source

Photobiomodulation as a contemporary antioxidant intervention in myocardial infarction

Experimental Physiology, EarlyView.
Abstract Myocardial infarction (MI) triggers a complex cascade of structural and functional alterations that frequently culminate in adverse cardiac remodelling and heart failure. Central to this process is the excessive production of reactive oxygen species (ROS), which disrupt mitochondrial function, impair calcium handling, and activate pro ...
Gabriel Matheus Da Silva Batista, Ighor Luiz Azevedo Teixeira, Ednei Luiz Antonio, Andrey Jorge Serra   +3 more
wiley   +1 more source

Invasive minimal Microvascular Resistance Is a New Index to Assess Microcirculatory Function Independent of Obstructive Coronary Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Background Coronary microcirculatory dysfunction portends a poor cardiovascular outcome. Invasive assessment of microcirculatory dysfunction by coronary flow reserve (CFR) and hyperemic microvascular resistance (HMR) is affected by coronary artery ...
Guus A. de Waard, Sukhjinder S. Nijjer, Martijn A. van Lavieren, Nina W. van der Hoeven, Ricardo Petraco, Tim P. van de Hoef, Mauro Echavarría‐Pinto, Sayan Sen, Peter M. van de Ven, Paul Knaapen, Javier Escaned, Jan J. Piek, Justin E. Davies, Niels van Royen   +13 more
doaj   +1 more source

Pre-treatment with compound Danshen dripping pills prevents lipid infusion-induced microvascular dysfunction in mice

Pharmaceutical Biology, 2020
Context Recent studies have shown compound Danshen dripping pills (CDDP) could improve microcirculation in ischemic/reperfusion injury and other microvascular disorders. The mechanism for CDDP’s role in microcirculation is not clear. Objective To explore
Yanda Zhang, Jian Zhao, Ru Ding, Wenhao Niu, Zhiqing He, Chun Liang   +5 more
doaj   +1 more source