Results 61 to 70 of about 1,009,765 (207)

The effect of renal denervation in microcirculation: focusing on coronary microvascular dysfunction

Future Cardiology
Arterial hypertension is one of the most prevalent cardiovascular pathologies worldwide. Considering the increased rates of uncontrolled hypertension and treatment non-adherence, catheter-based methods, with the most prominent being renal denervation, have been recently included in international guidelines for the management of the pathology, naming ...
Dimitriadis, Kyriakos, Pyrpyris, Nikolaos, Tatakis, Fotis, Kyriakoulis, Konstantinos, Pitsiori, Daphne Elpy, Beneki, Eirini, Fragkoulis, Christos, Konstantinidis, Dimitrios, Kollias, Anastasios, Aznaouridis, Konstantinos, Tsioufis, Konstantinos   +10 more
openaire   +3 more sources

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Diagnostic approach for coronary microvascular dysfunction in patients with chest pain and no obstructive coronary artery disease

, 2022
A large number of studies has demonstrated that abnormalities of coronary microcirculation may be responsible for both acute and chronic cardiac ischemic syndromes.
De Vita, Antonio, Crea, Filippo, Tritto, Isabella, Lanza, Gaetano Antonio, Pizzi, Carmine, Bergamaschi, Luca, Villano, Angelo, Morrone, Doralisa   +7 more
core   +2 more sources

Hemodynamic Significance of APEXCT Coronary Angiography Combined With Dynamic CT Myocardial Perfusion Imaging in Assessing Restenosis After Coronary Stenting

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to evaluate the hemodynamic significance of in‐stent restenosis (ISR) by using a combined anatomical‐functional approach with photon‐counting CT coronary angiography (APEX‐CT CTA) and dynamic CT myocardial perfusion imaging (CT‐MPI). We prospectively enrolled 239 symptomatic patients at least 9 months after PCI.
Liang‐Shi Wang, Tian Bai, Ji‐Zhou Yan, Peng‐Yu Guan, Li‐Juan Wen, Hong Guo, Tian‐Yu Zhang   +6 more
wiley   +1 more source

Coronary microcirculatory dysfunction and the causes of its development [PDF]

, 2009
Представлены современные литературные данные о механизмах развития коронарной микроциркуляторной дисфункции. Рассмотрены основные причины развития коронарной микроциркуляторной дисфункции, а также патологические состояния, при которых она встречается ...
Заривчацкая, И.Т., Белая, Н.В., Копица, Н.П., Титаренко, Н.В., Комир, И.И.   +4 more
core   +1 more source

Coronary microvascular dysfunction: pathophysiology, diagnosis, and therapeutic strategies across cardiovascular diseases

EXCLI Journal : Experimental and Clinical Sciences
Ischemic heart disease (IHD) is a leading cause of morbidity and mortality worldwide, presenting with acute and chronic coronary syndromes. Although coronary atherosclerosis is a major cause of IHD, many patients with angina or myocardial ischemia do ...
Vincenzo Scarica, Riccardo Rinaldi, Francesco Maria Animati, Matteo Manzato, Rocco Antonio Montone   +4 more
doaj   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

MRI-based in vivo detection of coronary microvascular dysfunction before alterations in cardiac function induced by short-term high-fat diet in mice

Scientific Reports, 2021
Endothelial dysfunction is one of the hallmarks of vascular abnormalities in metabolic diseases and has been repeatedly demonstrated in coronary and peripheral circulation in mice fed high-fat diet (HFD), particularly after long-term HFD.
Grzegorz Kwiatkowski, Anna Bar, Agnieszka Jasztal, Stefan Chłopicki   +3 more
doaj   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source